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Day One Biopharmaceuticals clinical trials

Source: ClinicalTrials.gov, U.S. National Library of Medicine — current trials in our USA, UK and Ireland registers with Day One Biopharmaceuticals as lead sponsor. Synced 26 Sep 2026
4Current trials
3Recruiting now
1Drug in these trials
3Trial registers
Maintained by Sreepriya Prasannan
MSc Digital Transformation of Life Sciences (Innopharma Education / Griffith College); MSc & BSc Botany HSE Spark Ignite 2026 — Top 14 finalist
Compiled from ClinicalTrials.gov and CTIS registry records · Last verified · Editorial standards
At a glance

Day One Biopharmaceuticals is the lead sponsor of 4 current clinical trials in our USA, UK and Ireland registers. 3 are recruiting patients now. The most common phase is Phase 3. The drugs named most often in its trials are Tovorafenib. The most-studied condition is Low-grade Glioma.

ClinicalTrials.gov trials by status

  • Recruiting375%
  • Active, closed125%

Trials by phase

  • Phase 3125%
  • Phase 2125%
  • Phase 1/2125%
  • Phase 1125%
01

Clinical trials sponsored by Day One Biopharmaceuticals

4 on ClinicalTrials.gov
StudyPhaseStatusStartRegisters
A Study to Evaluate Tovorafenib in Pediatric and Young Adult Participants With Relapsed or Progressive Low-Grade Glioma and Advance Solid Tumors
NCT04775485 · ClinicalTrials.gov ↗ · Low-grade Glioma, Advanced Solid Tumor
Phase 2 Recruiting 2021-04 UK, USA
A Study of Emiltatug Ledadotin (Emi-Le) in Participants With Solid Tumors
NCT05377996 · ClinicalTrials.gov ↗ · Triple Negative Breast Cancer, Breast Cancer, Endometrial Cancer
Phase 1/2 Recruiting 2022-08 USA
To Evaluate the Safety, Tolerability, Pharmacokinetics and Antitumor Activity of DAY301 in Participants With Locally Advanced or Metastatic Solid Tumors
NCT06752681 · ClinicalTrials.gov ↗ · Advanced or Metastatic Solid Tumors
Phase 1 Recruiting 2024-11 USA
DAY101 vs. Standard of Care Chemotherapy in Pediatric Participants With Low-Grade Glioma Requiring First-Line Systemic Therapy (LOGGIC/FIREFLY-2)
NCT05566795 · ClinicalTrials.gov ↗ · Low-grade Glioma, Rapidly Accelerated Fibrosarcoma (RAF) Altered Glioma, Pediatric Low-grade Glioma
Phase 3 Active, closed 2023-02 Ireland, UK, USA

Registers list studies that are recruiting, about to open, active but closed to enrolment, or enrolling by invitation. The UK and USA registers cover industry-sponsored studies only. Titles and statuses are copied from the registry as published.

02

Drugs in Day One Biopharmaceuticals trials

1 compound

Drugs and biologicals named as interventions in these trials, with the number of this sponsor's trials that name each one. Placebos and generic comparators are excluded.

03

Conditions in Day One Biopharmaceuticals trials

9 conditions
Low-grade Glioma2Rapidly Accelerated Fibrosarcoma (RAF) Altered Glioma1Pediatric Low-grade Glioma1Advanced Solid Tumor1Triple Negative Breast Cancer1Breast Cancer1Endometrial Cancer1Ovarian Cancer1Advanced or Metastatic Solid Tumors1
04

By trial register

RegisterTrialsRecruiting
Clinical trials in USA43
Clinical trials in UK21
Clinical trials in Ireland10

A trial with sites in more than one country appears in each of those registers.

05

Questions about Day One Biopharmaceuticals trials

How many clinical trials does Day One Biopharmaceuticals sponsor?

Day One Biopharmaceuticals is the lead sponsor of 4 current trials on ClinicalTrials.gov in our USA, UK and Ireland registers, as of the registry sync on 26 September 2026. Completed and withdrawn studies are not counted.

Are Day One Biopharmaceuticals trials recruiting?

Yes. 3 of its 4 ClinicalTrials.gov trials are recruiting. Eligibility and site contacts are on each trial's record. Only the study team can confirm whether a patient is eligible.

Which drugs is Day One Biopharmaceuticals testing?

Its current trials name 1 drug or biological as interventions. The most frequent are Tovorafenib (2). The number in brackets is how many of its trials name each drug.

Does Day One Biopharmaceuticals have clinical trials in Ireland?

Yes. 1 trial in our Ireland register (ClinicalTrials.gov). Some may be the same study registered in both. See the Irish clinical trials register for sites and contacts.

Where does this information come from?

Every trial, status, phase and condition on this page is copied from public ClinicalTrials.gov and EU CTIS records by a daily sync, grouped by the sponsor name each registry records. It says nothing about the organisation beyond its registered trials, and it is not medical advice.

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How this page is built

Everything on this page is copied from public registry records — it is not written from memory, and nothing here describes the organisation beyond its registered trials. Each trial links to its own record so you can check it yourself.

This page is built automatically: a daily sync job reads the registry records behind our trial registers and groups every current trial by its lead sponsor name, ignoring legal-form suffixes such as Inc. or Ltd. A small, hand-checked list joins the same organisation's different registry names (for example its EU legal entity). There is no AI drafting and no per-sponsor editorial pass. The “last verified” date above is the timestamp of that sync, not a review date. Our general editorial approach is described in our editorial standards and corrections policy. The the registries data on this page was last retrieved on 26 Sep 2026.

Please verify before you rely on this. This page is general information for life-science and pharmaceutical professionals. It is not medical advice, and it has not been reviewed by a clinician — our editorial team holds life-science qualifications, not clinical ones. It is not exhaustive and may not reflect the most recent label change. Always check the official prescribing information (US Prescribing Information or EU SmPC) and speak to your doctor or pharmacist before acting on anything here. Drugs in the same class are not automatically interchangeable, and approvals, brand names and indications differ between the US, the EU/Ireland (EMA/HPRA) and other regions. Spotted an error? Tell us — we correct promptly and log it.