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Chiesi Farmaceutici clinical trials

Source: ClinicalTrials.gov, U.S. National Library of Medicine and the EU Clinical Trials Information System (CTIS) — current trials in our UK, USA, China and EU (CTIS) registers with Chiesi Farmaceutici as lead sponsor. Synced 26 Sep 2026
18Current trials
11Recruiting now
5Drugs in these trials
4Trial registers
Maintained by Sreepriya Prasannan
MSc Digital Transformation of Life Sciences (Innopharma Education / Griffith College); MSc & BSc Botany HSE Spark Ignite 2026 — Top 14 finalist
Compiled from ClinicalTrials.gov and CTIS registry records · Last verified · Editorial standards
At a glance

Chiesi Farmaceutici is the lead sponsor of 18 current clinical trials in our UK, USA, China and EU (CTIS) registers. 11 are recruiting patients now. The most common phase is Observational. The drugs named most often in its trials are Metreleptin, CHF10196 and Dabigatran Etexilate. The most-studied condition is Fabry Disease.

ClinicalTrials.gov trials by status

  • Recruiting1179%
  • Not yet open214%
  • Active, closed17%

Trials by phase

  • Observational536%
  • Phase 3321%
  • Phase 1214%
  • Phase 2214%
  • Phase 1/217%
  • Phase 2/317%
01

Clinical trials sponsored by Chiesi Farmaceutici

14 on ClinicalTrials.gov
StudyPhaseStatusStartRegisters
A Study to Investigate the Safety, Tolerability, and Pharmacokinetics of Inhaled CHF6333 After Single Doses in Healthy Volunteers and After Single and Repeated Doses in Subjects With Bronchiectasis
NCT06166056 · Bronchiectasis
Phase 1/2 Recruiting 2023-11 UK
Therapeutic Equivalence of CHF5993 pMDI 100/6/12.5 µg HFA-152a in Subjects With Mild to Moderate Asthma
NCT07301736 · ClinicalTrials.gov ↗ · Asthma
Phase 2 Recruiting 2025-12 UK
Maternal and Postnatal Outcomes Study (MOS): A Global Observational Registry Assessing the Safety of Elfabrio® in Women With Fabry Disease and Their Infants During Pregnancy and Breastfeeding
NCT06941025 · ClinicalTrials.gov ↗ · Fabry Disease, Pregnancy, Pregnancy Complications
Observational Recruiting 2025-05 UK, USA
Efficacy and Safety of CHF 5993 100/6/12.5 μg HFA-152a pMDI in Patients With Asthma Uncontrolled on Medium Doses of Inhaled Corticosteroids in Combination With Long-acting ß2-agonists
NCT07546981 · ClinicalTrials.gov ↗ · Asthma
Phase 3 Recruiting 2026-06 China
PASS to Assess Cardiovascular and Cerebrovascular Events in COPD Patients Initiating Fixed Triple Therapy (DPI or pMDI)
NCT05652439 · ClinicalTrials.gov ↗ · Chronic Obstructive Pulmonary Disease
Observational Recruiting 2022-12 UK
A Multi-Country Observational Study of Safety and Effectiveness of Elfabrio® in Fabry Patients
NCT06663358 · ClinicalTrials.gov ↗ · Fabry Disease
Observational Recruiting 2024-11 UK, USA
A Study to Learn About the Safety and Effects of the Study Drug PRX-102 in Children and Adolescents With Fabry Disease
NCT06328608 · ClinicalTrials.gov ↗ · Fabry Disease
Phase 2/3 Recruiting 2025-07 UK, USA
MEASuRE: Metreleptin Effectiveness And Safety Registry
NCT02325674 · ClinicalTrials.gov ↗ · Generalised Lipodystrophy, Partial Lipodystrophy
Observational Recruiting 2016-10 UK, USA
Analysis of Velmanase Alfa (Lamzede®)'s Effects in the Body of Children With Alpha-Mannosidosis Under the Age 3
NCT06184503 · ClinicalTrials.gov ↗ · Alpha-Mannosidosis
Observational Recruiting 2025-02 USA
A Study to Find an Efficacious and Safe Dose of CHF10067 (Zampilimab) in Participants With Idiopathic Pulmonary Fibrosis
NCT07516951 · ClinicalTrials.gov ↗ · Idiopathic Pulmonary Fibrosis
Phase 2 Recruiting 2026-07 USA
Open-label Extension Study to Evaluate Metreleptin in Patients With Partial Lipodystrophy
NCT06679270 · ClinicalTrials.gov ↗ · Familial Partial Lipodystrophy
Phase 3 Recruiting 2024-10 USA
A Study in Healthy Male Participants to Compare How CHF10196 Affects How the Body Absorbs and Processes Two Commonly Used Medicines: Dabigatran, a Blood Thinner, and Rosuvastatin, a Medicine Used to Lower Cholesterol
NCT07744386 · ClinicalTrials.gov ↗ · Healthy Male Volunteers
Phase 1 Not yet open 2026-10 UK
A Study to Compare How CHF10196 (Florensocatib) is Absorbed Into the Blood When Given Alone and With a Drug That Reduces Stomach Acid in Healthy Male Participants
NCT07683793 · ClinicalTrials.gov ↗ · Healthy Volunteers
Phase 1 Not yet open 2026-10 UK
Study to Evaluate the Safety and Efficacy of Daily Subcutaneous Metreleptin Treatment in Subjects With PL
NCT05164341 · Partial Lipodystrophy
Phase 3 Active, closed 2021-12 USA

Registers list studies that are recruiting, about to open, active but closed to enrolment, or enrolling by invitation. The UK and USA registers cover industry-sponsored studies only. Titles and statuses are copied from the registry as published.

02

Chiesi Farmaceutici in the EU trials register (CTIS)

4 trials

Authorised or ongoing trials in the EU Clinical Trials Information System with Chiesi Farmaceutici as sponsor. Some are the same study as a ClinicalTrials.gov record above; the two registries share no common ID. Trials with a site in Ireland are listed first.

StudyPhaseStatusCountries
A prospective, open-label, non-randomized, multicentre trial to assess the safety and PD of Cangrelor as procedural platelet inhibitor in paediatric subjects from birth to <18 years of age undergoing diagnostic and/or therapeutic percutaneous vascular procedures for management of congenital heart disease
2025-523109-14-00 · CTIS ↗ · Cardiovascular Diseases
Phase 3 Authorised Netherlands, Germany, Portugal + 1 more
A pragmatic, phase IV, randomized, open-label, multinational, multicentre, 2-arm parallel group, prospective study comparing efficacy and safety of Single Inhaler ICS/LABA/LAMA (beclometasone/formoterol fumarate/glycopyrronium bromide [87/5/9 pMDI {BD/FF/GB - 100/6/12.5 µg}]) vs Single Inhaler ICS/LABA (beclometasone dipropionate plus formoterol fumarate [200/6 pMDI {BD/FF - 200/6 µg}]) in asthma subjects.
2025-524289-56-00 · CTIS ↗ · Respiratory Tract Diseases
Phase 4 Authorised Germany, Romania, Italy + 5 more
A Phase IIb, multicentre, randomised, doubleblind, placebocontrolled, three-arm parallel-group study to evaluate the efficacy, safety, and tolerability at Week 24 of 2 doses of CHF10067 (zampilimab) in participants with idiopathic pulmonary fibrosis
2024-514246-37-00 · CTIS ↗ · Respiratory Tract Diseases
Phase 2 Authorised Belgium, Germany, Italy + 8 more
A 52 week, randomized, double-blind, double dummy multinational, multicenter, active controlled, 2-arm parallel group trial comparing CHF 5993 100/6/12.5 µg pMDI (fixed combination of extrafine Beclomethasone Dipropionate plus Formoterol Fumarate plus Glycopyrronium Bromide) to Seretide® Evohaler® 125/25 µg pMDI (fixed combination of fluticasone propionate / salmeterol xinafoate) in adolescent subjects with asthma uncontrolled on medium doses of inhaled corticosteroids in combination with long acting ß2 agonists.
2024-514248-95-00 · CTIS ↗ · Respiratory Tract Diseases
Phase 3 Authorised Italy, Germany, Spain
03

Drugs in Chiesi Farmaceutici trials

5 compounds

Drugs and biologicals named as interventions in these trials, with the number of this sponsor's trials that name each one. Placebos and generic comparators are excluded.

04

Conditions in Chiesi Farmaceutici trials

13 conditions
Fabry Disease3Asthma2Partial Lipodystrophy2Bronchiectasis1Healthy Male Volunteers1Pregnancy1Pregnancy Complications1Chronic Obstructive Pulmonary Disease1Healthy Volunteers1Generalised Lipodystrophy1Alpha-Mannosidosis1Idiopathic Pulmonary Fibrosis1Familial Partial Lipodystrophy1
05

By trial register

RegisterTrialsRecruiting
Clinical trials in UK97
Clinical trials in USA87
Clinical trials in China11
EU register (CTIS)4—

A trial with sites in more than one country appears in each of those registers.

06

Other sponsors in Fabry Disease

SponsorTrials
Amicus Therapeutics4
Sangamo Therapeutics1
Idorsia Pharmaceuticals1
Shire1

Sponsors with the most current trials registered for this condition.

07

Questions about Chiesi Farmaceutici trials

How many clinical trials does Chiesi Farmaceutici sponsor?

Chiesi Farmaceutici is the lead sponsor of 14 current trials on ClinicalTrials.gov in our UK, USA and China registers, and 4 authorised or ongoing trials in the EU register (CTIS), as of the registry sync on 26 September 2026. Completed and withdrawn studies are not counted.

Are Chiesi Farmaceutici trials recruiting?

Yes. 11 of its 14 ClinicalTrials.gov trials are recruiting. Eligibility and site contacts are on each trial's record. Only the study team can confirm whether a patient is eligible.

Which drugs is Chiesi Farmaceutici testing?

Its current trials name 5 drugs and biologicals as interventions. The most frequent are Metreleptin (3), CHF10196 (2), Dabigatran Etexilate (1), Pantoprazole (1) and Rosuvastatin (1). The number in brackets is how many of its trials name each drug.

Where does this information come from?

Every trial, status, phase and condition on this page is copied from public ClinicalTrials.gov and EU CTIS records by a daily sync, grouped by the sponsor name each registry records. It says nothing about the organisation beyond its registered trials, and it is not medical advice.

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How this page is built

Everything on this page is copied from public registry records — it is not written from memory, and nothing here describes the organisation beyond its registered trials. Each trial links to its own record so you can check it yourself.

This page is built automatically: a daily sync job reads the registry records behind our trial registers and groups every current trial by its lead sponsor name, ignoring legal-form suffixes such as Inc. or Ltd. A small, hand-checked list joins the same organisation's different registry names (for example its EU legal entity). There is no AI drafting and no per-sponsor editorial pass. The “last verified” date above is the timestamp of that sync, not a review date. Our general editorial approach is described in our editorial standards and corrections policy. The the registries data on this page was last retrieved on 26 Sep 2026.

Please verify before you rely on this. This page is general information for life-science and pharmaceutical professionals. It is not medical advice, and it has not been reviewed by a clinician — our editorial team holds life-science qualifications, not clinical ones. It is not exhaustive and may not reflect the most recent label change. Always check the official prescribing information (US Prescribing Information or EU SmPC) and speak to your doctor or pharmacist before acting on anything here. Drugs in the same class are not automatically interchangeable, and approvals, brand names and indications differ between the US, the EU/Ireland (EMA/HPRA) and other regions. Spotted an error? Tell us — we correct promptly and log it.