C4 Therapeutics is the lead sponsor of 4 current clinical trials in our USA, UK and EU (CTIS) registers. 2 are recruiting patients now. The most common phase is Phase 1. The drugs named most often in its trials are Cemsidomide and Dexamethasone. The most-studied condition is Multiple Myeloma.
| Study | Phase | Status | Start | Registers |
|---|---|---|---|---|
|
A Study to Evaluate the Efficacy of Cemsidomide + Dexamethasone in Participants With Relapsed/Refractory Multiple Myeloma
NCT07284758 · ClinicalTrials.gov ↗ · Multiple Myeloma, Relapsed/Refractory Multiple Myeloma
Drugs: Cemsidomide, Dexamethasone |
Phase 2 | Recruiting | 2026-02 | UK, USA |
|
A Study to Learn About the Effects of Cemsidomide in Combination With Elranatamab in Relapsed/Refractory Multiple Myeloma Subjects
NCT07280013 · ClinicalTrials.gov ↗ · Multiple Myeloma (MM)
|
Phase 1 | Recruiting | 2026-02 | USA |
|
Study to Assess the Safety and Tolerability of CFT7455 in Relapsed/Refractory Non-Hodgkin's Lymphoma or Multiple Myeloma
NCT04756726 · ClinicalTrials.gov ↗ · Multiple Myeloma, Lymphoma, Non-Hodgkin's
Drugs: Cemsidomide, Dexamethasone |
Phase 1 | Active, closed | 2021-04 | USA |
Registers list studies that are recruiting, about to open, active but closed to enrolment, or enrolling by invitation. The UK and USA registers cover industry-sponsored studies only. Titles and statuses are copied from the registry as published.
Authorised or ongoing trials in the EU Clinical Trials Information System with C4 Therapeutics as sponsor. Some are the same study as a ClinicalTrials.gov record above; the two registries share no common ID. Trials with a site in Ireland are listed first.
| Study | Phase | Status | Countries |
|---|---|---|---|
|
A Phase 2, Open-Label, Single-Arm, Multicenter Study to Evaluate the Efficacy of Cemsidomide + Dexamethasone in Subjects With Relapsed/Refractory Multiple Myeloma (r/r MM)
2025-524181-26-00 · CTIS ↗ · Hemic and Lymphatic Diseases
Drug: Cemsidomide |
Phase 2 | Authorised | Italy, France, Spain + 1 more |
Drugs and biologicals named as interventions in these trials, with the number of this sponsor's trials that name each one. Placebos and generic comparators are excluded.
| Register | Trials | Recruiting |
|---|---|---|
| Clinical trials in USA | 3 | 2 |
| Clinical trials in UK | 1 | 1 |
| EU register (CTIS) | 1 | — |
A trial with sites in more than one country appears in each of those registers.
Sponsors with the most current trials registered for this condition.
C4 Therapeutics is the lead sponsor of 3 current trials on ClinicalTrials.gov in our USA and UK registers, and 1 authorised or ongoing trial in the EU register (CTIS), as of the registry sync on 26 September 2026. Completed and withdrawn studies are not counted.
Yes. 2 of its 3 ClinicalTrials.gov trials are recruiting. Eligibility and site contacts are on each trial's record. Only the study team can confirm whether a patient is eligible.
Its current trials name 2 drugs and biologicals as interventions. The most frequent are Cemsidomide (3) and Dexamethasone (2). The number in brackets is how many of its trials name each drug.
Every trial, status, phase and condition on this page is copied from public ClinicalTrials.gov and EU CTIS records by a daily sync, grouped by the sponsor name each registry records. It says nothing about the organisation beyond its registered trials, and it is not medical advice.
Everything on this page is copied from public registry records — it is not written from memory, and nothing here describes the organisation beyond its registered trials. Each trial links to its own record so you can check it yourself.
This page is built automatically: a daily sync job reads the registry records behind our trial registers and groups every current trial by its lead sponsor name, ignoring legal-form suffixes such as Inc. or Ltd. A small, hand-checked list joins the same organisation's different registry names (for example its EU legal entity). There is no AI drafting and no per-sponsor editorial pass. The “last verified” date above is the timestamp of that sync, not a review date. Our general editorial approach is described in our editorial standards and corrections policy. The the registries data on this page was last retrieved on 26 Sep 2026.