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Amylyx Pharmaceuticals clinical trials

Source: ClinicalTrials.gov, U.S. National Library of Medicine — current trials in our USA register with Amylyx Pharmaceuticals as lead sponsor. Synced 26 Sep 2026
3Current trials
1Recruiting now
0Drugs in these trials
1Trial register
Maintained by Sreepriya Prasannan
MSc Digital Transformation of Life Sciences (Innopharma Education / Griffith College); MSc & BSc Botany HSE Spark Ignite 2026 — Top 14 finalist
Compiled from ClinicalTrials.gov and CTIS registry records · Last verified · Editorial standards
At a glance

Amylyx Pharmaceuticals is the lead sponsor of 3 current clinical trials in our USA register. 1 is recruiting patients now. The most common phase is Phase 3. The most-studied condition is Post Bariatric Hypoglycemia.

ClinicalTrials.gov trials by status

  • Recruiting133%
  • Active, closed267%

Trials by phase

  • Phase 3133%
  • Phase 1133%
  • Phase 2133%
01

Clinical trials sponsored by Amylyx Pharmaceuticals

3 on ClinicalTrials.gov
StudyPhaseStatusStartRegisters
AMX0114 in Adult Participants With Amyotrophic Lateral Sclerosis
NCT06665165 · ClinicalTrials.gov ↗ · ALS
Phase 1 Recruiting 2025-04 USA
Avexitide for Treatment of Post-Bariatric Hypoglycemia
NCT06747468 · ClinicalTrials.gov ↗ · Post Bariatric Hypoglycemia
Phase 3 Active, closed 2025-04 USA
AMX0035 in Adult Patients With Wolfram Syndrome
NCT05676034 · ClinicalTrials.gov ↗ · Wolfram Syndrome
Phase 2 Active, closed 2023-03 USA

Registers list studies that are recruiting, about to open, active but closed to enrolment, or enrolling by invitation. The UK and USA registers cover industry-sponsored studies only. Titles and statuses are copied from the registry as published.

02

Conditions in Amylyx Pharmaceuticals trials

3 conditions
Post Bariatric Hypoglycemia1ALS1Wolfram Syndrome1
03

By trial register

RegisterTrialsRecruiting
Clinical trials in USA31

A trial with sites in more than one country appears in each of those registers.

04

Questions about Amylyx Pharmaceuticals trials

How many clinical trials does Amylyx Pharmaceuticals sponsor?

Amylyx Pharmaceuticals is the lead sponsor of 3 current trials on ClinicalTrials.gov in our USA register, as of the registry sync on 26 September 2026. Completed and withdrawn studies are not counted.

Are Amylyx Pharmaceuticals trials recruiting?

Yes. 1 of its 3 ClinicalTrials.gov trials is recruiting. Eligibility and site contacts are on each trial's record. Only the study team can confirm whether a patient is eligible.

Where does this information come from?

Every trial, status, phase and condition on this page is copied from public ClinicalTrials.gov and EU CTIS records by a daily sync, grouped by the sponsor name each registry records. It says nothing about the organisation beyond its registered trials, and it is not medical advice.

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How this page is built

Everything on this page is copied from public registry records — it is not written from memory, and nothing here describes the organisation beyond its registered trials. Each trial links to its own record so you can check it yourself.

This page is built automatically: a daily sync job reads the registry records behind our trial registers and groups every current trial by its lead sponsor name, ignoring legal-form suffixes such as Inc. or Ltd. A small, hand-checked list joins the same organisation's different registry names (for example its EU legal entity). There is no AI drafting and no per-sponsor editorial pass. The “last verified” date above is the timestamp of that sync, not a review date. Our general editorial approach is described in our editorial standards and corrections policy. The the registries data on this page was last retrieved on 26 Sep 2026.

Please verify before you rely on this. This page is general information for life-science and pharmaceutical professionals. It is not medical advice, and it has not been reviewed by a clinician — our editorial team holds life-science qualifications, not clinical ones. It is not exhaustive and may not reflect the most recent label change. Always check the official prescribing information (US Prescribing Information or EU SmPC) and speak to your doctor or pharmacist before acting on anything here. Drugs in the same class are not automatically interchangeable, and approvals, brand names and indications differ between the US, the EU/Ireland (EMA/HPRA) and other regions. Spotted an error? Tell us — we correct promptly and log it.