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Compound · clinical trials

Osimertinib Mesylate

Also listed in trial records as AZD9291
Source: ClinicalTrials.gov, U.S. National Library of Medicine — the 8 trials in our China and USA registers that name Osimertinib Mesylate as an intervention. Synced 24 Sep 2026
8Trials tracked
4Recruiting now
6Lead sponsors
2Country registers
Maintained by Sreepriya Prasannan
MSc Digital Transformation of Life Sciences (Innopharma Education / Griffith College); MSc & BSc Botany HSE Spark Ignite 2026 โ€” Top 14 finalist
Compiled from ClinicalTrials.gov registry records ยท Last verified ยท Editorial standards

Osimertinib Mesylate is named as a drug or biological intervention in 8 clinical trials in our China and USA trial registers, 4 of which are recruiting. Lead sponsors include AstraZeneca (2), Sichuan Baili Pharmaceutical Co., Ltd. (2) and Ascentage Pharma Group Inc. (1). Registered phases: Phase 3, Phase 2 and Phase 1. Conditions studied include Non-small Cell Lung Cancer; Stage IB-IIIA Non-small Cell Lung Carcinoma; Advanced Non Small Cell Lung Cancer.

01

Clinical trials of Osimertinib Mesylate

8 trials
NCT IDStudyPhaseStatusLead sponsorRegister
NCT06829459 A Study to Evaluate the Efficacy and Safety of Glumetinib Combined With Osimertinib Mesylate Versus Platinum-based Doublet Chemotherapy in Non-Small Cell Lung Cancer Patients After Resistance to EGFR-TKIs (ClinicalTrials.gov ↗)
Non-Small Cell Lung Cancer
Phase 3 Recruiting Shanghai JMT-Bio Inc. China
NCT06970639 A Study Evaluating Furmonertinib Plus Platinum-based Doublet Chemotherapy Versus Osimertinib in Patients With Epidermal Growth Factor Receptor (EGFR) Sensitizing Mutation-Positive Non-squamous Non-Small Cell Lung Cancer (NSCLC) and Brain Metastases (ClinicalTrials.gov ↗)
NSCLC Patients With Brain Metastasis
Phase 3 Recruiting Allist Pharmaceuticals, Inc. China
NCT06498986 A Study of BL-B01D1 in Combination With Osimertinib Mesylate Tablets in Patients With Locally Advanced or Metastatic Non-small Cell Lung Cancer (ClinicalTrials.gov ↗)
Non-small Cell Lung Cancer
Phase 2 Recruiting Sichuan Baili Pharmaceutical Co., Ltd. China
NCT07229729 A Study of SHR-A2102 in Combination With Other Anti-tumor Therapies for Resectable Non-small Cell Lung Cancer (ClinicalTrials.gov ↗)
Non-small Cell Lung Cancer
Phase 2 Recruiting Shanghai Hengrui Pharmaceutical Co., Ltd. China
NCT02511106 AZD9291 Versus Placebo in Patients With Stage IB-IIIA Non-small Cell Lung Carcinoma, Following Complete Tumour Resection With or Without Adjuvant Chemotherapy.
Stage IB-IIIA Non-small Cell Lung Carcinoma
Phase 3 Active, closed AstraZeneca USA, China
NCT05880706 A Study of BL-B01D1 and BL-B01D1 in Combination With Osimertinib Mesylate Tablets in Patients With Locally Advanced or Metastatic Non-small Cell Lung Cancer (ClinicalTrials.gov ↗)
Non-small Cell Lung Cancer
Phase 2 Active, closed Sichuan Baili Pharmaceutical Co., Ltd. China
NCT02143466 AZD9291 in Combination With Ascending Doses of Novel Therapeutics (ClinicalTrials.gov ↗)
Advanced Non Small Cell Lung Cancer
Phase 1 Active, closed AstraZeneca USA
NCT04001777 A Study of APG-1252 Plus Osimertinib(AZD9291) in EGFR TKI Resistant NSCLC Patients (ClinicalTrials.gov ↗)
EGFR Positive Non-small Cell Lung Cancer
Phase 1 Active, closed Ascentage Pharma Group Inc. China

Registers list studies that are recruiting, about to open, active but closed to enrolment, or enrolling by invitation. The UK and USA registers cover industry-sponsored studies only. Trial titles and statuses are copied from the registry as published.

02

Conditions studied

6 conditions
Condition (as registered)Trials
Non-small Cell Lung Cancer3
Stage IB-IIIA Non-small Cell Lung Carcinoma1
Advanced Non Small Cell Lung Cancer1
EGFR Positive Non-small Cell Lung Cancer1
NSCLC Patients With Brain Metastasis1
Non-Small Cell Lung Cancer1
03

Sponsors

lead sponsor per trial
Lead sponsorTrials
AstraZeneca2
Sichuan Baili Pharmaceutical Co., Ltd.2
Ascentage Pharma Group Inc.1
Allist Pharmaceuticals, Inc.1
Shanghai JMT-Bio Inc.1
Shanghai Hengrui Pharmaceutical Co., Ltd.1
04

Trials by country register

RegisterOsimertinib Mesylate trials
Clinical trials in China7
Clinical trials in USA2

A trial with sites in more than one country appears in each of those registers.

How this page is built

Everything on this page is copied from public ClinicalTrials.gov registry records โ€” it is not written from memory, and nothing here describes how Osimertinib Mesylate works or whether it is effective. Each trial links to its own record so you can check it yourself.

This page is built automatically: a daily sync job reads the registry records behind our country trial registers, collects every trial that lists Osimertinib Mesylate (or a registered synonym) as a drug or biological intervention, and tabulates the registry fields directly. Placebos and generic comparators are excluded. There is no AI drafting and no per-compound editorial pass, and the page has not been clinically reviewed. The “last verified” date above is the timestamp of that sync, not a review date. Our general editorial approach is described in our editorial standards and corrections policy. The ClinicalTrials.gov data on this page was last retrieved on 24 Sep 2026.

Please verify before you rely on this. This page is general information for life-science and pharmaceutical professionals. It is not medical advice, and it has not been reviewed by a clinician โ€” our editorial team holds life-science qualifications, not clinical ones. It is not exhaustive and may not reflect the most recent label change. Always check the official prescribing information (US Prescribing Information or EU SmPC) and speak to your doctor or pharmacist before acting on anything here. Drugs in the same class are not automatically interchangeable, and approvals, brand names and indications differ between the US, the EU/Ireland (EMA/HPRA) and other regions. Spotted an error? Tell us โ€” we correct promptly and log it.