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Compound · clinical trials

Brenipatide clinical trials

Also listed in trial records as LY3537031
Source: ClinicalTrials.gov, U.S. National Library of Medicine — the 14 trials in our USA, China, UK and India registers that name Brenipatide as an intervention. Synced 25 Sep 2026
14Current trials
10Recruiting now
1Lead sponsor
4Country registers
Maintained by Sreepriya Prasannan
MSc Digital Transformation of Life Sciences (Innopharma Education / Griffith College); MSc & BSc Botany HSE Spark Ignite 2026 โ€” Top 14 finalist
Compiled from ClinicalTrials.gov registry records ยท Last verified ยท Editorial standards
At a glance

Brenipatide is named as an intervention in 14 current clinical trials in our USA, China, UK and India registers. 10 are recruiting patients now. The most common phase is Phase 2. The lead sponsor is Eli Lilly and Company. The most-studied condition is Alcohol Use Disorder.

Trials by status

  • Recruiting1071%
  • Not yet open214%
  • Active, closed214%

Trials by phase

  • Phase 2857%
  • Phase 3429%
  • Phase 1214%
01

Clinical trials of Brenipatide

14 trials
StudyPhaseStatusLead sponsorRegisters
A Study of Brenipatide in Participants With Alcohol Use Disorder
NCT07219953 · ClinicalTrials.gov ↗ · Alcohol Use Disorder
Phase 3 Recruiting Eli Lilly and Company UK, USA, China
A Study of Brenipatide in Participants With Moderate-to-Severe Alcohol Use Disorder
NCT07219966 · Alcohol Use Disorder
Phase 3 Recruiting Eli Lilly and Company UK, USA, China
A Study of Brenipatide in Adult Participants With Major Depressive Disorder
NCT07412756 · ClinicalTrials.gov ↗ · Depressive Disorder, Major
Phase 3 Recruiting Eli Lilly and Company UK, USA, China
A Study to Evaluate Brenipatide Compared With Placebo in Adult Participants With Uncontrolled Moderate to Severe Asthma
NCT07219173 · Asthma
Phase 2 Recruiting Eli Lilly and Company USA, India, China
A Study of Brenipatide in Adults Who Quit Smoking Cigarettes and Want to Avoid Relapse
NCT07223840 · ClinicalTrials.gov ↗ · Smoking
Phase 2 Recruiting Eli Lilly and Company USA, China
A Study of Brenipatide in Adult Participants With Bipolar Disorder (RENEW-Bipolar-1)
NCT07286175 · ClinicalTrials.gov ↗ · Bipolar Disorder
Phase 2 Recruiting Eli Lilly and Company USA, India, China
A Study of Brenipatide in Adult Participants With Schizophrenia
NCT07410507 · ClinicalTrials.gov ↗ · Schizophrenia
Phase 2 Recruiting Eli Lilly and Company USA, India, China
A Study of Brenipatide in Participants With Opioid Use Disorder
NCT07420283 · ClinicalTrials.gov ↗ · Opioid Use Disorder
Phase 2 Recruiting Eli Lilly and Company UK, USA
A Study of Brenipatide (LY3537031) in Participants With Irritable Bowel Syndrome-Diarrhea (IBS-D)
NCT07545759 · ClinicalTrials.gov ↗ · Irritable Bowel Syndrome, Diarrhea
Phase 2 Recruiting Eli Lilly and Company UK, USA, China
A Study of Brenipatide (LY3537031) in Participants With Irritable Bowel Syndrome-Constipation (IBS-C)
NCT07545772 · ClinicalTrials.gov ↗ · Irritable Bowel Syndrome, Constipation
Phase 2 Recruiting Eli Lilly and Company UK, USA, China
A Study of Brenipatide (LY3537031) in Adult Participants With Major Depressive Disorder
NCT07775300 · ClinicalTrials.gov ↗ · Depressive Disorder, Major
Phase 3 Not yet open Eli Lilly and Company UK, USA, China
A Study of Brenipatide (LY3537031) in Adult Participants With Moderate-to-Severe Chronic Obstructive Pulmonary Disease (COPD)
NCT07759245 · Pulmonary Disease, Chronic Obstructive
Phase 2 Not yet open Eli Lilly and Company UK, USA, India, China
A Study of LY3537031 in Overweight, Obese, and Healthy Participants
NCT06606106 · ClinicalTrials.gov ↗ · Overweight, Obesity
Phase 1 Active, closed Eli Lilly and Company USA
A Study of Brenipatide (LY3537031) in Healthy Participants With Overweight or Obesity
NCT07476118 · ClinicalTrials.gov ↗ · Obesity, Overweight
Phase 1 Active, closed Eli Lilly and Company USA

Registers list studies that are recruiting, about to open, active but closed to enrolment, or enrolling by invitation. The UK and USA registers cover industry-sponsored studies only. Trial titles and statuses are copied from the registry as published.

02

Conditions studied with Brenipatide

13 conditions
Alcohol Use Disorder2Depressive Disorder, Major2Obesity2Overweight2Irritable Bowel Syndrome2Pulmonary Disease, Chronic Obstructive1Opioid Use Disorder1Asthma1Schizophrenia1Bipolar Disorder1Smoking1Diarrhea1
All 13 conditions
Condition (as registered)Trials
Alcohol Use Disorder2
Depressive Disorder, Major2
Obesity2
Overweight2
Irritable Bowel Syndrome2
Pulmonary Disease, Chronic Obstructive1
Opioid Use Disorder1
Asthma1
Schizophrenia1
Bipolar Disorder1
Smoking1
Diarrhea1
Constipation1
03

Sponsors

lead sponsor per trial
Lead sponsorTrials
Eli Lilly and Company14
04

By country register

RegisterTrialsRecruiting
Clinical trials in USA1410
Clinical trials in China119
Clinical trials in UK86
Clinical trials in India43

A trial with sites in more than one country appears in each of those registers.

05

Questions about Brenipatide trials

How many clinical trials are testing Brenipatide?

14 current trials in our USA, China, UK and India registers name Brenipatide (also registered as LY3537031) as a drug or biological intervention, as of the registry sync on 25 September 2026. Completed and withdrawn studies are not counted.

Are Brenipatide trials recruiting patients?

Yes. 10 of the 14 trials are recruiting: 10 with sites in USA, 9 with sites in China, 6 with sites in UK and 3 with sites in India. Eligibility and site contacts are on each trial's record. Only the study team can confirm whether a patient is eligible.

Who sponsors Brenipatide clinical trials?

The lead sponsor is Eli Lilly and Company. The number in brackets is how many trials each organisation leads.

Where does this information come from?

Every trial, status, phase and sponsor on this page is copied from public ClinicalTrials.gov records by a daily sync. Nothing here describes how Brenipatide works or whether it is effective, and it is not medical advice.

How this page is built

Everything on this page is copied from public ClinicalTrials.gov registry records โ€” it is not written from memory, and nothing here describes how Brenipatide works or whether it is effective. Each trial links to its own record so you can check it yourself.

This page is built automatically: a daily sync job reads the registry records behind our country trial registers, collects every trial that lists Brenipatide (or a registered synonym) as a drug or biological intervention, and tabulates the registry fields directly. Placebos and generic comparators are excluded. There is no AI drafting and no per-compound editorial pass, and the page has not been clinically reviewed. The “last verified” date above is the timestamp of that sync, not a review date. Our general editorial approach is described in our editorial standards and corrections policy. The ClinicalTrials.gov data on this page was last retrieved on 25 Sep 2026.

Please verify before you rely on this. This page is general information for life-science and pharmaceutical professionals. It is not medical advice, and it has not been reviewed by a clinician โ€” our editorial team holds life-science qualifications, not clinical ones. It is not exhaustive and may not reflect the most recent label change. Always check the official prescribing information (US Prescribing Information or EU SmPC) and speak to your doctor or pharmacist before acting on anything here. Drugs in the same class are not automatically interchangeable, and approvals, brand names and indications differ between the US, the EU/Ireland (EMA/HPRA) and other regions. Spotted an error? Tell us โ€” we correct promptly and log it.