Levoleucovorin is named as a drug or biological intervention in 5 clinical trials in our USA, China, UK and Ireland trial registers, 4 of which are recruiting. Lead sponsors include Merck Sharp & Dohme LLC (3), Seagen, a wholly owned subsidiary of Pfizer (1) and Taiho Oncology, Inc. (1). Registered phases: Phase 1/2, Phase 3 and Phase 2. Conditions studied include Colorectal Neoplasms; Colorectal Cancer; Pancreatic Ductal Adenocarcinoma.
Registers list studies that are recruiting, about to open, active but closed to enrolment, or enrolling by invitation. The UK and USA registers cover industry-sponsored studies only. Trial titles and statuses are copied from the registry as published.
| Condition (as registered) | Trials |
|---|---|
| Colorectal Neoplasms | 1 |
| Colorectal Cancer | 1 |
| Pancreatic Ductal Adenocarcinoma | 1 |
| Biliary Tract Cancer | 1 |
| Gastroesophageal Junction | 1 |
| Gastroesophageal Adenocarcinoma | 1 |
| Esophageal Neoplasms | 1 |
| Esophageal Cancer | 1 |
| Esophageal Squamous Cell Carcinoma | 1 |
| Locally Advanced Unresectable or Metastatic Solid Tumors Including Esophageal Cancer | 1 |
| Esophageal Adenocarcinoma | 1 |
| Esophageal Squamous Cell Cancer | 1 |
| Siewert Type 1 GEJ Cancer | 1 |
| Lead sponsor | Trials |
|---|---|
| Merck Sharp & Dohme LLC | 3 |
| Seagen, a wholly owned subsidiary of Pfizer | 1 |
| Taiho Oncology, Inc. | 1 |
| Register | Levoleucovorin trials |
|---|---|
| Clinical trials in USA | 5 |
| Clinical trials in China | 4 |
| Clinical trials in UK | 2 |
| Clinical trials in Ireland | 1 |
A trial with sites in more than one country appears in each of those registers.
Everything on this page is copied from public ClinicalTrials.gov registry records — it is not written from memory, and nothing here describes how Levoleucovorin works or whether it is effective. Each trial links to its own record so you can check it yourself.
This page is built automatically: a daily sync job reads the registry records behind our country trial registers, collects every trial that lists Levoleucovorin (or a registered synonym) as a drug or biological intervention, and tabulates the registry fields directly. Placebos and generic comparators are excluded. There is no AI drafting and no per-compound editorial pass, and the page has not been clinically reviewed. The “last verified” date above is the timestamp of that sync, not a review date. Our general editorial approach is described in our editorial standards and corrections policy. The ClinicalTrials.gov data on this page was last retrieved on 24 Sep 2026.