Ireland
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Priya Life Science Compound trial record
Compound · clinical trials

HLX43 1 clinical trials

Source: ClinicalTrials.gov, U.S. National Library of Medicine — the 11 trials in our China and USA registers that name HLX43 1 as an intervention. Synced 9 Nov 2026
11Current trials
9Recruiting now
1Lead sponsor
2Country registers
At a glance

HLX43 1 is named as an intervention in 11 current clinical trials in our China and USA registers. 9 are recruiting patients now. The most common phase is Phase 2. The lead sponsor is Shanghai Henlius Biotech. The most-studied condition is Non Small Cell Lung Cancer.

Patient leaflets for HLX43 1

The package leaflet is the official guide for patients that comes with every medicine. These links go to the regulators that publish it.

  • UK
    United Kingdom: Search MHRA Products
    Patient information leaflets and SmPCs for UK-licensed products.
  • US
    United States: Search DailyMed
    FDA-approved labels, including patient and medication guides.

Leaflets differ between brands and countries; always read the one that comes with your own medicine. This is regulatory information, not medical advice.

Trials by status

  • Recruiting982%
  • Not yet open218%

Trials by phase

  • Phase 2982%
  • Phase 1/2218%
01

Clinical trials of HLX43 1

11 trials
StudyPhaseStatusLead sponsorRegisters
A Phase II Clinical Study to Evaluate HLX43 in Patients With Locally Advanced or Metastatic HCC Failed or Intolerance to Standard Therapy
NCT06742892 · ClinicalTrials.gov ↗ · Carcinoma, Hepatocellular
Phase 2 Recruiting Shanghai Henlius Biotech China
A Phase II Study to Evaluate HLX43 in Subjects With Recurrent/Metastatic Nasopharyngeal Carcinoma Failed or Intolerance to Second-line Therapy
NCT06839066 · ClinicalTrials.gov ↗ · Nasopharyngeal Carcinoma (NPC)
Phase 2 Recruiting Shanghai Henlius Biotech China
A Phase II Clinical Study to Evaluate HLX43 in Subjects With Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma
NCT06857279 · ClinicalTrials.gov ↗ · Carcinoma of Head and/or Neck
Phase 2 Recruiting Shanghai Henlius Biotech China
A Phase II Clinical Study to Evaluate HLX43 in Subjects With Advanced Non-small Cell Lung Cancer (NSCLC)
NCT06907615 · Non Small Cell Lung Cancer
Phase 2 Recruiting Shanghai Henlius Biotech USA, China
Phase II, Open-label, Multicenter Study to Evaluate the Efficacy and Safety of HLX43 (an Anti-PD-L1 ADC) in Subjects With Advanced Colorectal Cancer
NCT07106892 · ClinicalTrials.gov ↗ · Colorectal Cancer (CRC)
Phase 2 Recruiting Shanghai Henlius Biotech China
Phase II, Open-label, Multicenter Study to Evaluate the Efficacy and Safety of HLX43 (an Anti-PD-L1 ADC) in Subjects With Advanced Gastric or Gastroesophageal Junction Adenocarcinoma
NCT07115485 · ClinicalTrials.gov ↗ · Gastric or Gastroesophageal Junction Adenocarcinoma
Phase 2 Recruiting Shanghai Henlius Biotech China
A Phase II Clinical Study to Evaluate HLX43 in Combination With Serplulimab in Subjects With Advanced Lung Cancer
NCT07253142 · ClinicalTrials.gov ↗ · Non Small Cell Lung Cancer, Small Cell Lung Cancer
Phase 2 Recruiting Shanghai Henlius Biotech China
A Phase II Study to Evaluate the Efficacy and Safety of HLX43 + Serplulimab as Neoadjuvant Therapy in Subjects With NSCLC
NCT07269782 · ClinicalTrials.gov ↗ · Non Small Cell Lung Cancer
Phase 2 Recruiting Shanghai Henlius Biotech China
A Phase Ib/II Clinical Study to Evaluate HLX43 in Combination With Serplulimab in Patients With Advanced/Metastatic Solid Tumors
NCT06848699 · ClinicalTrials.gov ↗ · Solid Tumor Cancer, Non Small Cell Lung Cancer
Phase 1/2 Recruiting Shanghai Henlius Biotech China
Phase II Study of HLX43 Monotherapy or Combined With Immune Checkpoint Inhibitors in Patients With Locally Advanced, Recurrent, or Metastatic Triple-negative Breast Cancer.
NCT07487519 · ClinicalTrials.gov ↗ · Breast Cancer (Triple Negative Breast Cancer (TNBC))
Phase 2 Not yet open Shanghai Henlius Biotech China
A Phase Ib/II Study to Evaluate HLX43 Combined With HLX07 or Serplulimab in Patients With Advanced or Metastatic Colorectal Cancer
NCT07358585 · ClinicalTrials.gov ↗ · Colon Cancer Adenocarcinoma
Phase 1/2 Not yet open Shanghai Henlius Biotech China

Registers list studies that are recruiting, about to open, active but closed to enrolment, or enrolling by invitation. The UK and USA registers cover industry-sponsored studies only. Trial titles and statuses are copied from the registry as published.

02

Conditions studied with HLX43 1

10 conditions
Non Small Cell Lung Cancer4Colorectal Cancer (CRC)1Gastric or Gastroesophageal Junction Adenocarcinoma1Carcinoma, Hepatocellular1Small Cell Lung Cancer1Carcinoma of Head and/or Neck1Solid Tumor Cancer1Breast Cancer (Triple Negative Breast Cancer (TNBC))1Nasopharyngeal Carcinoma (NPC)1Colon Cancer Adenocarcinoma1
03

Sponsors

lead sponsor per trial
Lead sponsorTrials
Shanghai Henlius Biotech11
04

By country register

RegisterTrialsRecruiting
Clinical trials in China119
Clinical trials in USA11

A trial with sites in more than one country appears in each of those registers.

05

Related compounds

06

Questions about HLX43 1 trials

How many clinical trials are testing HLX43 1?

11 current trials in our China and USA registers name HLX43 1 as a drug or biological intervention, as of the registry sync on 9 November 2026. Completed and withdrawn studies are not counted.

Are HLX43 1 trials recruiting patients?

Yes. 9 of the 11 trials are recruiting: 9 with sites in China and 1 with sites in USA. Eligibility and site contacts are on each trial's record. Only the study team can confirm whether a patient is eligible.

Who sponsors HLX43 1 clinical trials?

The lead sponsor is Shanghai Henlius Biotech. The number in brackets is how many trials each organisation leads.

Where does this information come from?

Every trial, status, phase and sponsor on this page is copied from public ClinicalTrials.gov records by a daily sync. Nothing here describes how HLX43 1 works or whether it is effective, and it is not medical advice.

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How this page is built

Everything on this page is copied from public ClinicalTrials.gov registry records — it is not written from memory, and nothing here describes how HLX43 1 works or whether it is effective. Each trial links to its own record so you can check it yourself.

This page is built automatically: a daily sync job reads the registry records behind our country trial registers, collects every trial that lists HLX43 1 (or a registered synonym) as a drug or biological intervention, and tabulates the registry fields directly. Placebos and generic comparators are excluded. There is no AI drafting and no per-compound editorial pass, and the page has not been clinically reviewed. The “last verified” date above is the timestamp of that sync, not a review date. Our general editorial approach is described in our editorial standards and corrections policy. The ClinicalTrials.gov data on this page was last retrieved on 9 Nov 2026. How every register is built: methodology · fixes we have made: corrections log.

Please verify before you rely on this. This page is general information for life-science and pharmaceutical professionals. It is not medical advice, and it has not been reviewed by a clinician — our editorial team holds life-science qualifications, not clinical ones. It is not exhaustive and may not reflect the most recent label change. Always check the official prescribing information (US Prescribing Information or EU SmPC) and speak to your doctor or pharmacist before acting on anything here. Drugs in the same class are not automatically interchangeable, and approvals, brand names and indications differ between the US, the EU/Ireland (EMA/HPRA) and other regions. Spotted an error? Tell us — we correct promptly and log it.