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Compound · clinical trials

HLX43 clinical trials

Source: ClinicalTrials.gov, U.S. National Library of Medicine — the 4 trials in our China and USA registers that name HLX43 as an intervention. Synced 25 Sep 2026
4Current trials
3Recruiting now
1Lead sponsor
2Country registers
Maintained by Sreepriya Prasannan
MSc Digital Transformation of Life Sciences (Innopharma Education / Griffith College); MSc & BSc Botany HSE Spark Ignite 2026 โ€” Top 14 finalist
Compiled from ClinicalTrials.gov registry records ยท Last verified ยท Editorial standards
At a glance

HLX43 is named as an intervention in 4 current clinical trials in our China and USA registers. 3 are recruiting patients now. The most common phase is Phase 2. The lead sponsor is Shanghai Henlius Biotech. The most-studied condition is Advanced/Metastatic Malignant Solid Tumors.

Trials by status

  • Recruiting375%
  • By invitation125%

Trials by phase

  • Phase 2250%
  • Phase 1125%
  • Phase 2/3125%
01

Clinical trials of HLX43

4 trials
StudyPhaseStatusLead sponsorRegisters
A Global Phase II/III Clinical Study to Evaluate the Efficacy and Safety of HLX43 Monotherapy or HLX43 in Combination With HLX07 Versus Docetaxel in Advanced or Metastatic Squamous Non-Small Cell Lung Cancer
NCT07459751 · ClinicalTrials.gov ↗ · Advanced or Metastatic Squamous Non-Small Cell Lung Cancer
Phase 2/3 Recruiting Shanghai Henlius Biotech China
A Phase II Clinical Study to Evaluate HLX43 in Patients With Recurrent/Metastatic ESCC Failed or Intolerance to Standard Therapy
NCT06769113 · ClinicalTrials.gov ↗ · Esophageal Cancer
Phase 2 Recruiting Shanghai Henlius Biotech China
A Phase II Clinical Study to Evaluate the Efficacy and Safety of HLX43 (Anti-PD-L1 ADC) in Patients With Advanced Gynecological Malignant Tumors
NCT06769152 · ClinicalTrials.gov ↗ · Cervical Cancer, Ovarian Cancer
Phase 2 Recruiting Shanghai Henlius Biotech China
A Phase I Study to Evaluate the Safety, Tolerability, and PK of HLX43 in Advanced/Metastatic Solid Tumors
NCT06115642 · ClinicalTrials.gov ↗ · Advanced/Metastatic Malignant Solid Tumors
Phase 1 By invitation Shanghai Henlius Biotech USA, China

Registers list studies that are recruiting, about to open, active but closed to enrolment, or enrolling by invitation. The UK and USA registers cover industry-sponsored studies only. Trial titles and statuses are copied from the registry as published.

02

Conditions studied with HLX43

5 conditions
Advanced/Metastatic Malignant Solid Tumors1Advanced or Metastatic Squamous Non-Small Cell Lung Cancer1Cervical Cancer1Ovarian Cancer1Esophageal Cancer1
03

Sponsors

lead sponsor per trial
Lead sponsorTrials
Shanghai Henlius Biotech4
04

By country register

RegisterTrialsRecruiting
Clinical trials in China43
Clinical trials in USA10

A trial with sites in more than one country appears in each of those registers.

05

Related compounds

06

Questions about HLX43 trials

How many clinical trials are testing HLX43?

4 current trials in our China and USA registers name HLX43 as a drug or biological intervention, as of the registry sync on 25 September 2026. Completed and withdrawn studies are not counted.

Are HLX43 trials recruiting patients?

Yes. 3 of the 4 trials are recruiting: 3 with sites in China. Eligibility and site contacts are on each trial's record. Only the study team can confirm whether a patient is eligible.

Who sponsors HLX43 clinical trials?

The lead sponsor is Shanghai Henlius Biotech. The number in brackets is how many trials each organisation leads.

Where does this information come from?

Every trial, status, phase and sponsor on this page is copied from public ClinicalTrials.gov records by a daily sync. Nothing here describes how HLX43 works or whether it is effective, and it is not medical advice.

How this page is built

Everything on this page is copied from public ClinicalTrials.gov registry records โ€” it is not written from memory, and nothing here describes how HLX43 works or whether it is effective. Each trial links to its own record so you can check it yourself.

This page is built automatically: a daily sync job reads the registry records behind our country trial registers, collects every trial that lists HLX43 (or a registered synonym) as a drug or biological intervention, and tabulates the registry fields directly. Placebos and generic comparators are excluded. There is no AI drafting and no per-compound editorial pass, and the page has not been clinically reviewed. The “last verified” date above is the timestamp of that sync, not a review date. Our general editorial approach is described in our editorial standards and corrections policy. The ClinicalTrials.gov data on this page was last retrieved on 25 Sep 2026.

Please verify before you rely on this. This page is general information for life-science and pharmaceutical professionals. It is not medical advice, and it has not been reviewed by a clinician โ€” our editorial team holds life-science qualifications, not clinical ones. It is not exhaustive and may not reflect the most recent label change. Always check the official prescribing information (US Prescribing Information or EU SmPC) and speak to your doctor or pharmacist before acting on anything here. Drugs in the same class are not automatically interchangeable, and approvals, brand names and indications differ between the US, the EU/Ireland (EMA/HPRA) and other regions. Spotted an error? Tell us โ€” we correct promptly and log it.