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Compound · clinical trials

Efimosfermin alfa clinical trials

Source: ClinicalTrials.gov, U.S. National Library of Medicine — the 6 trials in our USA register that name Efimosfermin alfa as an intervention. Synced 25 Sep 2026
6Current trials
6Recruiting now
1Lead sponsor
1Country register
Maintained by Sreepriya Prasannan
MSc Digital Transformation of Life Sciences (Innopharma Education / Griffith College); MSc & BSc Botany HSE Spark Ignite 2026 โ€” Top 14 finalist
Compiled from ClinicalTrials.gov registry records ยท Last verified ยท Editorial standards
At a glance

Efimosfermin alfa is named as an intervention in 6 current clinical trials in our USA register. 6 are recruiting patients now. The most common phase is Phase 3. The lead sponsor is GlaxoSmithKline. The most-studied condition is Non-alcoholic Fatty Liver Disease.

Trials by status

  • Recruiting6100%

Trials by phase

  • Phase 3467%
  • Phase 2117%
  • Phase 1117%
01

Clinical trials of Efimosfermin alfa

6 trials
StudyPhaseStatusLead sponsorRegisters
A Clinical Study to Investigate the Safety and Tolerability of Efimosfermin Alfa Injection in Participants With Known or Suspected F2- or F3-stage MASH
NCT07221188 · ClinicalTrials.gov ↗ · Non-alcoholic Fatty Liver Disease
Phase 3 Recruiting GlaxoSmithKline USA
A Pivotal Clinical Study to Investigate Efimosfermin Alfa in Participants With Biopsy-confirmed F2- or F3-stage MASH
NCT07221227 · ClinicalTrials.gov ↗ · Non-alcoholic Fatty Liver Disease
Phase 3 Recruiting GlaxoSmithKline USA
A Pivotal Clinical Study to Investigate the Safety and Efficacy of Efimosfermin Compared With Placebo in Adult Participants With Compensated Cirrhosis Due to Metabolic Dysfunction-associated Steatohepatitis (MASH)
NCT07701993 · ClinicalTrials.gov ↗ · Metabolic Dysfunction-associated Steatohepatitis
Phase 3 Recruiting GlaxoSmithKline USA
A Study to Investigate Safety and Efficacy of Efimosfermin Compared With Placebo in Adult Participants With Compensated Cirrhosis Due to Metabolic Dysfunction-associated Steatohepatitis (MASH)
NCT07704892 · ClinicalTrials.gov ↗ · Metabolic Dysfunction-associated Steatohepatitis
Phase 3 Recruiting GlaxoSmithKline USA
A Study to Investigate the Safety and Efficacy of Efimosfermin Alfa Compared With Placebo in Adult Participants With Alcohol-related Liver Disease (ALD)
NCT07791043 · ClinicalTrials.gov ↗ · Liver Diseases, Alcoholic
Phase 2 Recruiting GlaxoSmithKline USA
A Study of Efimosfermin Alfa in Adults With Hepatic Impairment
NCT07358546 · ClinicalTrials.gov ↗ · Non-alcoholic Fatty Liver Disease
Phase 1 Recruiting GlaxoSmithKline USA

Registers list studies that are recruiting, about to open, active but closed to enrolment, or enrolling by invitation. The UK and USA registers cover industry-sponsored studies only. Trial titles and statuses are copied from the registry as published.

02

Conditions studied with Efimosfermin alfa

3 conditions
Non-alcoholic Fatty Liver Disease3Metabolic Dysfunction-associated Steatohepatitis2Liver Diseases, Alcoholic1
03

Sponsors

lead sponsor per trial
Lead sponsorTrials
GlaxoSmithKline6
04

By country register

RegisterTrialsRecruiting
Clinical trials in USA66

A trial with sites in more than one country appears in each of those registers.

05

Related compounds

06

Questions about Efimosfermin alfa trials

How many clinical trials are testing Efimosfermin alfa?

6 current trials in our USA register name Efimosfermin alfa as a drug or biological intervention, as of the registry sync on 25 September 2026. Completed and withdrawn studies are not counted.

Are Efimosfermin alfa trials recruiting patients?

Yes. 6 of the 6 trials are recruiting: 6 with sites in USA. Eligibility and site contacts are on each trial's record. Only the study team can confirm whether a patient is eligible.

Who sponsors Efimosfermin alfa clinical trials?

The lead sponsor is GlaxoSmithKline. The number in brackets is how many trials each organisation leads.

Where does this information come from?

Every trial, status, phase and sponsor on this page is copied from public ClinicalTrials.gov records by a daily sync. Nothing here describes how Efimosfermin alfa works or whether it is effective, and it is not medical advice.

How this page is built

Everything on this page is copied from public ClinicalTrials.gov registry records โ€” it is not written from memory, and nothing here describes how Efimosfermin alfa works or whether it is effective. Each trial links to its own record so you can check it yourself.

This page is built automatically: a daily sync job reads the registry records behind our country trial registers, collects every trial that lists Efimosfermin alfa (or a registered synonym) as a drug or biological intervention, and tabulates the registry fields directly. Placebos and generic comparators are excluded. There is no AI drafting and no per-compound editorial pass, and the page has not been clinically reviewed. The “last verified” date above is the timestamp of that sync, not a review date. Our general editorial approach is described in our editorial standards and corrections policy. The ClinicalTrials.gov data on this page was last retrieved on 25 Sep 2026.

Please verify before you rely on this. This page is general information for life-science and pharmaceutical professionals. It is not medical advice, and it has not been reviewed by a clinician โ€” our editorial team holds life-science qualifications, not clinical ones. It is not exhaustive and may not reflect the most recent label change. Always check the official prescribing information (US Prescribing Information or EU SmPC) and speak to your doctor or pharmacist before acting on anything here. Drugs in the same class are not automatically interchangeable, and approvals, brand names and indications differ between the US, the EU/Ireland (EMA/HPRA) and other regions. Spotted an error? Tell us โ€” we correct promptly and log it.