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Compound · clinical trials

Clonidine clinical trials

Also listed in trial records as Catapresan, Catapres
Source: ClinicalTrials.gov, U.S. National Library of Medicine — the 8 trials in our Sweden, Canada, China, Denmark, Australia, Brazil and Egypt registers that name Clonidine as an intervention. Synced 26 Sep 2026
8Current trials
6Recruiting now
6Lead sponsors
7Country registers
Maintained by Sreepriya Prasannan
MSc Digital Transformation of Life Sciences (Innopharma Education / Griffith College); MSc & BSc Botany HSE Spark Ignite 2026 โ€” Top 14 finalist
Compiled from ClinicalTrials.gov registry records ยท Last verified ยท Editorial standards
At a glance

Clonidine is named as an intervention in 8 current clinical trials in our Sweden, Canada, China, Denmark, Australia, Brazil and Egypt registers. 6 are recruiting patients now. The most common phase is Phase 4. The sponsor with the most trials is Region Skane (2). The most-studied condition is Hypertension.

Trials by status

  • Recruiting675%
  • Not yet open113%
  • Active, closed113%

Trials by phase

  • Phase 4338%
  • Not applicable225%
  • Observational225%
  • Phase 2/3113%
01

Clinical trials of Clonidine

8 trials
StudyPhaseStatusLead sponsorRegisters
Efficacy of Clonidine in Reducing Craving in Inpatients With Cocaine and Crack Use Disorder
NCT07313371 · ClinicalTrials.gov ↗ · Cocaine Use Disorder, Crack Abuse or Dependence
Phase 4 Recruiting University of Sao Paulo General Hospital Brazil
Combination of Nerve Blocks and Local Infiltration Analgesia in Knee Arthroplasty
NCT07350252 · ClinicalTrials.gov ↗ · Osteo Arthritis of the Knee
Phase 4 Recruiting Region Skane Sweden
The PREVENT AGITATION Trial II - Children โ‰ค1 Year
NCT05091242 · ClinicalTrials.gov ↗ · Emergence Delirium
Phase 2/3 Recruiting Rigshospitalet, Denmark Denmark, Australia
Lemborexant vs Zopiclone vs Clonidine for Insomnia Treatment in Chronic Pain Patients
NCT05618002 · ClinicalTrials.gov ↗ · Chronic Insomnia, Chronic Pain
Observational Recruiting Salem Anaesthesia Pain Clinic Canada
Kratom Use Disorder Management Using Clonidine and/or Buprenorphine
NCT05883358 · ClinicalTrials.gov ↗ · Withdrawal Syndrome
Observational Recruiting Salem Anaesthesia Pain Clinic Canada
Premedication in Children: a Clinical Trial Comparing Oral Ketamine and Oral Clonidine With Respect to Sedation Level and Opioid Consumption in Pediatrics Undergoing Elective Lower Abdominal Day-case Surgery.
NCT07461376 · ClinicalTrials.gov ↗ · Pediatric Sedation, Clonidine Sedation, Ketamine Sedation
Not applicable Recruiting Cairo University Egypt
Effects and Safety of Clonidine Patch on Young and Middle-aged Smokers With Mild Hypertension
NCT05416840 · ClinicalTrials.gov ↗ · Hypertension
Phase 4 Not yet open Jing Liu China
Comparison Between Blocks or Not in Joint Arthroplasty
NCT06230081 · ClinicalTrials.gov ↗ · Osteoarthritis of the Knee or Hip
Not applicable Active, closed Region Skane Sweden

Registers list studies that are recruiting, about to open, active but closed to enrolment, or enrolling by invitation. The UK and USA registers cover industry-sponsored studies only. Trial titles and statuses are copied from the registry as published.

02

Clonidine across our data

Ireland · EU · US

The same active substance in our other registers, matched by its exact name. Each entry links to the register record it comes from.

Licensed in Ireland (HPRA)

3 single-substance products containing Clonidine on the HPRA medicines list.

All 3 Irish products →

Supply shortages

No entry for Clonidine in the EMA, FDA or German BfArM shortage lists we track.

03

Conditions studied with Clonidine

12 conditions
Hypertension1Osteo Arthritis of the Knee1Osteoarthritis of the Knee or Hip1Emergence Delirium1Withdrawal Syndrome1Chronic Insomnia1Chronic Pain1Cocaine Use Disorder1Crack Abuse or Dependence1Pediatric Sedation1Clonidine Sedation1Ketamine Sedation1
04

Sponsors

lead sponsor per trial
Lead sponsorTrials
Region Skane2
Salem Anaesthesia Pain Clinic2
Jing Liu1
Rigshospitalet, Denmark1
University of Sao Paulo General Hospital1
Cairo University1
05

By country register

RegisterTrialsRecruiting
Clinical trials in Sweden21
Clinical trials in Canada22
Clinical trials in China10
Clinical trials in Denmark11
Clinical trials in Australia11
Clinical trials in Brazil11
Clinical trials in Egypt11

A trial with sites in more than one country appears in each of those registers.

06

Related compounds

07

Questions about Clonidine trials

How many clinical trials are testing Clonidine?

8 current trials in our Sweden, Canada, China, Denmark, Australia, Brazil and Egypt registers name Clonidine as a drug or biological intervention, as of the registry sync on 26 September 2026. Completed and withdrawn studies are not counted.

Are Clonidine trials recruiting patients?

Yes. 6 of the 8 trials are recruiting: 1 with sites in Sweden, 2 with sites in Canada, 1 with sites in Denmark, 1 with sites in Australia, 1 with sites in Brazil and 1 with sites in Egypt. Eligibility and site contacts are on each trial's record. Only the study team can confirm whether a patient is eligible.

Who sponsors Clonidine clinical trials?

Region Skane (2), Salem Anaesthesia Pain Clinic (2), Jing Liu (1) and Rigshospitalet, Denmark (1), among 6 lead sponsors in total. The number in brackets is how many trials each organisation leads.

Is Clonidine licensed in Ireland?

Yes. The HPRA medicines list includes 3 single-substance products containing Clonidine, for example Catapres Ampoules 150 micrograms in 1 ml Solution for Injection (Glenwood GmbH). A licence does not mean a product is currently marketed or reimbursed; see each product's record.

Is there a Clonidine shortage?

Not in the lists we track: Clonidine has no entry in the EMA, FDA or German BfArM shortage registers as of their latest sync.

Where does this information come from?

Every trial, status, phase and sponsor on this page is copied from public ClinicalTrials.gov records by a daily sync. Nothing here describes how Clonidine works or whether it is effective, and it is not medical advice.

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How this page is built

Everything on this page is copied from public ClinicalTrials.gov registry records โ€” it is not written from memory, and nothing here describes how Clonidine works or whether it is effective. Each trial links to its own record so you can check it yourself.

This page is built automatically: a daily sync job reads the registry records behind our country trial registers, collects every trial that lists Clonidine (or a registered synonym) as a drug or biological intervention, and tabulates the registry fields directly. Placebos and generic comparators are excluded. There is no AI drafting and no per-compound editorial pass, and the page has not been clinically reviewed. The “last verified” date above is the timestamp of that sync, not a review date. Our general editorial approach is described in our editorial standards and corrections policy. The ClinicalTrials.gov data on this page was last retrieved on 26 Sep 2026.

Please verify before you rely on this. This page is general information for life-science and pharmaceutical professionals. It is not medical advice, and it has not been reviewed by a clinician โ€” our editorial team holds life-science qualifications, not clinical ones. It is not exhaustive and may not reflect the most recent label change. Always check the official prescribing information (US Prescribing Information or EU SmPC) and speak to your doctor or pharmacist before acting on anything here. Drugs in the same class are not automatically interchangeable, and approvals, brand names and indications differ between the US, the EU/Ireland (EMA/HPRA) and other regions. Spotted an error? Tell us โ€” we correct promptly and log it.