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Compound · clinical trials

CDK4/6 inhibitor

Source: ClinicalTrials.gov, U.S. National Library of Medicine — the 9 trials in our China register that name CDK4/6 inhibitor as an intervention. Synced 24 Sep 2026
9Trials tracked
7Recruiting now
5Lead sponsors
1Country register
Maintained by Sreepriya Prasannan
MSc Digital Transformation of Life Sciences (Innopharma Education / Griffith College); MSc & BSc Botany HSE Spark Ignite 2026 โ€” Top 14 finalist
Compiled from ClinicalTrials.gov registry records ยท Last verified ยท Editorial standards

CDK4/6 inhibitor is named as a drug or biological intervention in 9 clinical trials in our China trial register, 7 of which are recruiting. Lead sponsors include Fudan University (5), Peking Union Medical College (1) and Wenjin Yin (1). Registered phases: Phase 2, Phase 3 and Observational. Conditions studied include Breast Cancer; Advanced Breast Cancer; Adjuvant Therapy.

01

Clinical trials of CDK4/6 inhibitor

9 trials
NCT IDStudyPhaseStatusLead sponsorRegister
NCT06447623 Apatinib Combined With cdk4/6i in First-line Treatment for HR+/HER2- SNF4 Subtype Breast Cancer (ClinicalTrials.gov ↗)
Advanced Breast Cancer, HR+/HER2- Breast Cancer
Phase 3 Recruiting Fudan University China
NCT07019363 CDK4/6 Inhibitors Combined With Standard Adjuvant Endocrine Therapy in High-Risk, HR+/HER2+ Early Breast Cancer Patients(CHESS)
Breast Cancer, Adjuvant Therapy
Phase 3 Recruiting Fudan University China
NCT06145308 Precision Treatment of Recurrent/Metastatic Salivary Gland Carcinoma Guided by Molecular Typing (ClinicalTrials.gov ↗)
Salivary Gland Carcinoma, Precision Therapy
Phase 2 Recruiting Peking Union Medical College China
NCT07117630 An Open-Label, Bayesian Adaptive Phase II Clinical Study in HR+/HER2- Advanced Breast Cancer After Progression on Standard Therapy (ClinicalTrials.gov ↗)
Breast Cancer
Phase 2 Recruiting Fudan University China
NCT07180160 Iparomlimab and Tuvonralimab (QL1706) in Patients With HR-positive, HER2-negative Advanced Breast Cancer (ClinicalTrials.gov ↗)
Advanced Breast Cancer
Phase 2 Recruiting Wenjin Yin China
NCT07666555 A Phase II Clinical Study of the Efficacy and Safety of Culmerciclib Rechallenge in HR-positive, HER2-negative Breast Cancer Patients With Resistance to First-line Endocrine Therapy. (ClinicalTrials.gov ↗)
Breast Cancer
Phase 2 Recruiting Fudan University China
NCT05795335 CDK4/6 Inhibitors in Patients With Hormone Receptor-positive Advanced Breast Cancer (ClinicalTrials.gov ↗)
Breast Cancer
Observational Recruiting RenJi Hospital China
NCT06996093 Chemotherapy Omission in HR-positive/HER2-negative Breast Cancer With Lymph Node Negative Disease Receiving Adjuvant Endocrine Therapy and CDK4/6 Inhibitor (ClinicalTrials.gov ↗)
Breast Cancer
Phase 3 Not yet open Fudan University China
NCT06791161 A Multicenter Prospective Cohort Study of Adjuvant Therapy for BRCA1/2 Mutated Hormone Receptor-positive HER2-negative Early High-risk Breast Cancer (ClinicalTrials.gov ↗)
Breast
Observational By invitation Cancer Institute and Hospital, Chinese Academy of Medical Sciences China

Registers list studies that are recruiting, about to open, active but closed to enrolment, or enrolling by invitation. The UK and USA registers cover industry-sponsored studies only. Trial titles and statuses are copied from the registry as published.

02

Conditions studied

7 conditions
Condition (as registered)Trials
Breast Cancer5
Advanced Breast Cancer2
Adjuvant Therapy1
HR+/HER2- Breast Cancer1
Salivary Gland Carcinoma1
Precision Therapy1
Breast1
03

Sponsors

lead sponsor per trial
Lead sponsorTrials
Fudan University5
Peking Union Medical College1
Wenjin Yin1
Cancer Institute and Hospital, Chinese Academy of Medical Sciences1
RenJi Hospital1
04

Trials by country register

RegisterCDK4/6 inhibitor trials
Clinical trials in China9

A trial with sites in more than one country appears in each of those registers.

How this page is built

Everything on this page is copied from public ClinicalTrials.gov registry records โ€” it is not written from memory, and nothing here describes how CDK4/6 inhibitor works or whether it is effective. Each trial links to its own record so you can check it yourself.

This page is built automatically: a daily sync job reads the registry records behind our country trial registers, collects every trial that lists CDK4/6 inhibitor (or a registered synonym) as a drug or biological intervention, and tabulates the registry fields directly. Placebos and generic comparators are excluded. There is no AI drafting and no per-compound editorial pass, and the page has not been clinically reviewed. The “last verified” date above is the timestamp of that sync, not a review date. Our general editorial approach is described in our editorial standards and corrections policy. The ClinicalTrials.gov data on this page was last retrieved on 24 Sep 2026.

Please verify before you rely on this. This page is general information for life-science and pharmaceutical professionals. It is not medical advice, and it has not been reviewed by a clinician โ€” our editorial team holds life-science qualifications, not clinical ones. It is not exhaustive and may not reflect the most recent label change. Always check the official prescribing information (US Prescribing Information or EU SmPC) and speak to your doctor or pharmacist before acting on anything here. Drugs in the same class are not automatically interchangeable, and approvals, brand names and indications differ between the US, the EU/Ireland (EMA/HPRA) and other regions. Spotted an error? Tell us โ€” we correct promptly and log it.