ALN-4324 is named as a drug or biological intervention in 2 clinical trials in our USA trial register, 1 of which is recruiting. The lead sponsor is Alnylam Pharmaceuticals. Registered phases: Phase 2 and Phase 1/2. Conditions studied include Type 2 Diabetes Mellitus (T2DM); Obese or Overweight Healthy Volunteers.
| NCT ID | Study | Phase | Status |
|---|---|---|---|
| NCT07465224 | A Study to Evaluate ALN-4324 on Insulin Sensitivity in Adults With Type 2 Diabetes Mellitus (ClinicalTrials.gov ↗) Type 2 Diabetes Mellitus (T2DM) |
Phase 2 | Recruiting |
| NCT06845202 | A Study to Evaluate ALN-4324 in Overweight to Obese Healthy Volunteers and in Overweight to Obese Patients With T2DM (ClinicalTrials.gov ↗) Obese or Overweight Healthy Volunteers, Type 2 Diabetes Mellitus (T2DM) |
Phase 1/2 | Active, closed |
Registers list studies that are recruiting, about to open, active but closed to enrolment, or enrolling by invitation. The UK and USA registers cover industry-sponsored studies only. Trial titles and statuses are copied from the registry as published.
| Condition (as registered) | Trials |
|---|---|
| Type 2 Diabetes Mellitus (T2DM) | 2 |
| Obese or Overweight Healthy Volunteers | 1 |
| Lead sponsor | Trials |
|---|---|
| Alnylam Pharmaceuticals | 2 |
| Register | ALN-4324 trials |
|---|---|
| Clinical trials in USA | 2 |
A trial with sites in more than one country appears in each of those registers.
Everything on this page is copied from public ClinicalTrials.gov registry records — it is not written from memory, and nothing here describes how ALN-4324 works or whether it is effective. Each trial links to its own record so you can check it yourself.
This page is built automatically: a daily sync job reads the registry records behind our country trial registers, collects every trial that lists ALN-4324 (or a registered synonym) as a drug or biological intervention, and tabulates the registry fields directly. Placebos and generic comparators are excluded. There is no AI drafting and no per-compound editorial pass, and the page has not been clinically reviewed. The “last verified” date above is the timestamp of that sync, not a review date. Our general editorial approach is described in our editorial standards and corrections policy. The ClinicalTrials.gov data on this page was last retrieved on 24 Sep 2026.