The objective of this study is to evaluate the safety and efficacy of AGN-151586 for the treatment of moderate to severe forehead lines (FHL) in adult participants.
Eligibility
Sex
ALL
Min age
18 Years
Max age
—
Healthy volunteers
No
Inclusion Criteria:
* Participant must have moderate (Grade 2) or severe (Grade 3) forehead lines (FHL) at maximum eyebrow elevation as assessed by the subject and investigator using Forehead Lines Severity Scale (FHLSS) at Screening visit and Baseline Day 1 visit.
* Participant must have moderate (Grade 2) or severe (Grade 3) glabellar lines (GL) at maximum frown as assessed by the subject and investigator using Allergan Glabellar Lines Severity Scale (AGLSS) at Screening visit and Baseline Day 1 visit.
* Sufficient visual acuity without the use of eyeglasses (contact lens use is acceptable) to accurately assess their FHL and GL in investigator's opinion.
Exclusion Criteria:
* Clinically relevant or significant ECG abnormalities.
* Active infection or dermatological condition at any of the treatment injection sites.
Primary outcome measure(s)
Number of Participants with Adverse Events (AEs) — Up to Approximately 42 Days An AE is defined as any untoward medical occurrence in a patient or clinical investigation in which a participant is administered a pharmaceutical product which does not necessarily have a causal relationship with this treatment.
Trial sites (5)
Facility
City
Region
Status
Eye Research Foundation /ID# 282193
Newport Beach
California
Recruiting
Private Practice - Dr. Steven G. Yoelin /ID# 282334
Newport Beach
California
Recruiting
Luxurgery /ID# 282336
New York
New York
Recruiting
Wilmington Dermatology Center /ID# 282192
Wilmington
North Carolina
Recruiting
Austin Institute for Clinical Research - Pflugerville /ID# 282195
This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.
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