🇮🇪Ireland
16°C Partly Cloudy · Dublin
Live Updates
--:--:-- IST
Writer Login
Latest
Clinical Trials in the USA / NCT07681102
Enrolling by invitation Not applicable

Amplitude Modulation Frequency Comparison in Kilohertz Transcranial Magnetic Perturbation (kTMP) for Chronic Stroke

NCT07681102 · tracked via the Priya Life Science USA tracker
Sponsor
Magnetic Tides
Phase
Not applicable
Started
2026-02-10
Last updated
2026-07-06

Condition(s) studied

Stroke

Investigational drug(s) / intervention(s)

kTMP

kTMP: A new non-invasive brain stimulation tool

Study summary

Stroke is a leading cause of disability with many patients suffering chronic motor function impairments that affect their day-to-day activities. The goal of this proposal is to provide a first assessment of the feasibility and efficacy of an innovative non-invasive brain stimulation system, kTMP, in the treatment of motor impairment following stroke.

Eligibility

Sex
ALL
Min age
18 Years
Max age
80 Years
Healthy volunteers
No
Inclusion Criteria: 1. Adults aged 18-80 years who have a history of a unilateral stroke ≥ 12 m prior to enrollment. 2. Fugl-Meyer Assessment: Upper Extremity (FMA UE) score 20-55. 3. Ability to communicate, understand, and give appropriate consent. Participants can follow two-step commands. 4. Motor evoked potentials in a hand muscle when stimulating ipsilesional cortex with suprathreshold single-pulse TMS (MEP positive). Exclusion Criteria: 1. Participants with moderate or severe cognitive impairment (MoCA \< 18). 2. Participants with sensory deficits FMA-S ≥ 6/12 (with proprioception ≥ 2/4). 3. Language impairment or behavioral disorder that interferes with their ability to adhere to the protocol or to provide informed consent. 4. Individuals who have a serious uncontrolled medical condition, including but not limited to severe cardiovascular and cardiopulmonary disease. 5. Pregnancy or plans to become pregnant during the study period. 6. Botulinum toxin injections of the affected upper extremity within 3 months prior to onset of study assessments/testing through the last visit. 7. Severe spasticity of the affected upper limb (Modified Ashworth ≥ 3). 8. Absolute contraindications related to non-invasive brain stimulation, including: History of seizures in the last 12 months while taking anti-epilepsy medication Presence of any metal implants in the head (excluding the mouth), such as cortical stimulators and DBS, clips, coils, shunts, stents or skull plates, cochlear implants Permanent eye liner or head tattoos Implanted electronics such as pacemakers, defibrillators, intrathecal baclofen pumps or vagus nerve stimulator History of experiencing a serious adverse event during a previous transcranial magnetic stimulation (TMS) session

Primary outcome measure(s)

Trial sites (1)

FacilityCityRegionStatus
Magnetic Tides Inc. Berkeley California

More Magnetic Tides trials in the USA

Other trials for the same condition

Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT07681102 on ClinicalTrials.gov ↗ ← All trials in the USA