A Research Study on How Well Different Doses of the Medicine UBT251 Help People Living With Overweight or Obesity
Condition(s) studied
Investigational drug(s) / intervention(s)
UBT251: UBT251 injection will be administered subcutaneously in a lifted fold of the abdominal skin.
Placebo: Placebo matched to UBT251 injection will be administered subcutaneously in a lifted fold of the abdominal skin.
Study summary
The purpose of this clinical study is to find out if UBT251 is safe and effective for treating people who are living with overweight or obesity. Participants will get either UBT251 (the treatment being tested) or Placebo (a treatment that has no active medicine in it), which treatment participants get is decided by chance.
Eligibility
Primary outcome measure(s)
- Part A - Number of treatment emergent adverse events (TEAEs) — From baseline (week 0) to end of study (week 33)
Measured as Number of events. - Part B - Relative change in body weight — From baseline (week 0) to end of treatment (week 28)
Measured as percentage of body weight. - Part C- AUC; the area under the UBT251 plasma concentration time curve — From pre-dose on Day 1 until completion of the end of study visit (Day 43)
Measured as hour\*nanomoles per liter (h\*nmol/L)
Trial sites (3)
| Facility | City | Region | Status |
|---|---|---|---|
| Altasciences Clinical LA, Inc. | Cypress | California | Recruiting |
| Altasciences Clinical Kansas, Inc. | Overland Park | Kansas | Recruiting |
| Altasciences Clinical Company, Inc | Montreal | Quebec | Recruiting |
More Novo Nordisk A/S trials in the USA
Other trials for the same condition
This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.
View NCT07395687 on ClinicalTrials.gov ↗ ← All trials in the USA