The goal of this clinical trial is to learn if Daily Nouri Hormone Balance Probiotic blend can improve metabolic, inflammatory, and symptom outcomes in women.
Participants will:
* Take the probiotic blend or placebo every day for 12 weeks
* Complete virtual assessments and report symptoms throughout the study
Eligibility
Sex
FEMALE
Min age
18 Years
Max age
45 Years
Healthy volunteers
Accepted
Inclusion Criteria:
* Self-reported irregular menstrual cycles, defined as one or more of the following:
* Cycle length typically \>35 days OR \<21 days
* Fewer than 9 menstrual periods in the past year
* Unpredictable cycle timing (varies by \>7 days month-to-month)
* Irregular cycles present for ≥6 months
* One or more of the following hormonal balance concerns: skin, unwanted hair growth, hair thinning, weight concerns)
* Self-reported emotional symptoms that fluctuate with menstrual cycle, including:
* Mood swings or irritability
* Feelings of stress or tension
* Low mood or feeling down
* Difficulty with emotional regulation
* Not currently using hormonal therapies, metformin, GLP-1 receptor agonists, or anti-androgens.
* If taking supplements for menstrual/hormonal support: willing to discontinue for 2-week washout before baseline
* Weight stable (+ 5 pounds) for the past 2 months, not planning to start a new diet, exercise program, or medications during study
* Able to provide electronic informed consent.
* Willing to complete online surveys and at-home DBS sample collection.
* Negative home pregnancy test at baseline.
* Access to a computer or smartphone and reliable internet connection.
Primary outcome measure(s)
Women's Health Quality of Life Scores — From baseline to week 12 Women's Health Quality of Life as measured by changes in total and domains scores on the Health-Related Quality of Life Questionnaire for Polycystic Ovary Syndrome-26 (PCOSQ-26). Response Scale: 7-Point Likert Scale Per-Item Range: minimum: 1, maximum: 7, where higher scores indicate better outcomes.
This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.
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