Glepaglutide 10 mg: Administered twice weekly by subcutaneous injection for a maximum of 24 months
The purpose of this study is to understand the safety and efficacy of twice weekly glepaglutide 10 mg in adult patients with short bowel syndrome (SBS), who were previously enrolled in the EASE SBS 2 or EASE SBS 3 trials. Participants currently on these trials will be able to continue their glepaglutide treatment by enrolling in this EASE SBS 6 extension trial. The trial includes a 24-month treatment period, followed by a 4-week safety follow-up period. Participants will attend trial visits, where they may undergo heart tests (electrocardiogram (ECG)), vital sign checks, colonoscopies, blood and urine tests, and physical exams.
| Facility | City | Region | Status |
|---|---|---|---|
| Mayo Clinic - PPDS | Rochester | Minnesota | |
| Lied Transplant Center at Nebraska Medical Center | Omaha | Nebraska | |
| Cleveland Clinic-9500 Euclid Ave | Cleveland | Ohio | |
| Vanderbilt University Medical Center-Tennesse-1211 21st Ave S | Nashville | Tennessee | |
| UZ Leuven - PPDS | Leuven | Belgium | |
| LHSC - University Hospital | London | Ontario | |
| AP-HP - Hôpital Beaujon | Clichy | Hauts-de-Seine | |
| Universitätsklinikum Frankfurt | Frankfurt am Main | Hesse | |
| Universitätsmedizin Rostock | Rostock | Mecklenburg-Vorpommern | |
| Universitätsklinikum Bonn | Bonn | North Rhine-Westphalia | |
| Charité - Universitätsmedizin Berlin | Berlin | State of Berlin | |
| Asklepios Klinik St. Georg | Hamburg | Germany | |
| Szpital Skawina sp. z o.o. im. Stanley Dudricka | Skawina | Lesser Poland Voivodeship | |
| Samodzielny Publiczny Szpitala Kliniczny im. Prof. Witolda Orlowskiego CMKP | Warsaw | Masovian Voivodeship | |
| Wojewódzki Szpital Specjalistycznyo im. M. Pirogowa w Lodzi | Lodz | Poland | |
| St Mark's Hospital (Central Middlesex Hospital) | Ealing | United Kingdom |
This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.
View NCT07228403 on ClinicalTrials.gov ↗ ← All trials in the USA