Brief Electrical Stimulation Therapy: 10-minutes of electrical stimulation to repaired nerve
Digital Nerve Repair: Standard of care surgical repair of digital nerve injury as determined by health care provider.
Study summary
The goal of this clinical study is to evaluate if a period of electrical stimulation delivered during the surgical repair procedure can speed up nerve healing.
Eligibility
Sex
ALL
Min age
18 Years
Max age
80 Years
Healthy volunteers
No
Inclusion Criteria:
* Age 18-80 years
* Candidate for surgical intervention under general anesthesia.
* Require primary nerve injury repair in at least 1 digital nerve.
* Following resection, have a resulting nerve gap of ≤ 10mm.
* Able to complete tension-free end-to-end direct repair, or repair with a conduit, autograft, or allograft with a length ≤15mm
* Signed and dated informed consent form.
Exclusion Criteria:
* Severe comorbid conditions, such as arrhythmia or congestive heart failure, preventing surgery under general anesthesia.
* Nerve repair occurring \>1 month post-injury.
* Incomplete nerve transection.
* Injury requiring replantation of target digit
* Injury distal to the distal interphalangeal joint.
* Injury proximal to branching into the proper or common digital nerves.
* Injuries to both digital arteries of an affected digit.
* History of neuropathy, diabetic neuropathy, or any other known neuropathy
* History of chronic ischemic condition of the upper extremity
* Cognitive impairment preventing the ability to provide consent, follow post-operative instructions, or complete clinical assessments.
Primary outcome measure(s)
Two Point Discrimination — 2 weeks - 9 months Evaluation of sensory function based on ability to discern two point of contact for different distances between the contacts (2-15mm). Evaluated at each follow-up visit.
Trial sites (5)
Facility
City
Region
Status
Indiana Hand to Shoulder Center
Indianapolis
Indiana
Recruiting
University of Missouri Department of Orthopaedic Surgery
Columbia
Missouri
Recruiting
Washington University in St Louis, Department of Orthopedic Surgery
St Louis
Missouri
Recruiting
The Ohio State Univeristy - Department of Plastic and Reconstructive Surgery
Columbus
Ohio
Recruiting
Harborview Medical Center - University of Washington
This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.
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