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Clinical Trials in the USA / NCT06735833
Recruiting Not applicable

MMA Embolization for Refractory Chronic Migraine

NCT06735833 · tracked via the Priya Life Science USA tracker
Sponsor
Cerenovus, Part of DePuy Synthes Products, Inc.
Phase
Not applicable
Started
2025-04-23
Last updated
2026-08-28

Condition(s) studied

Migraine Disorders

Investigational drug(s) / intervention(s)

Middle Meningeal Artery embolization

Middle Meningeal Artery embolization: Bilateral middle meningeal artery embolization using TRUFILL n-BCA liquid embolic system

Study summary

This is a prospective, multi-center, feasibility study to investigate safety and effectiveness of TRUFILL n-BCA liquid embolic system in bilateral middle meningeal artery (MMA) embolization for the treatment of refractory chronic migraine.

Eligibility

Sex
ALL
Min age
18 Years
Max age
65 Years
Healthy volunteers
No
Participant Inclusion Criteria, Candidates for this study must meet ALL the following inclusion criteria: 1. Patient is between 18 and 65 years of age (inclusive) at the time of consent 2. Age of onset of Chronic Migraine \<= 64 years 3. Age of onset of migraine diagnosis \< 50 years 4. Patient has a current diagnosis of refractory migraine 5. Patient has a current diagnosis of Chronic migraine Participant Exclusion Criteria, Candidates will be excluded from participation if ANY of the following apply: 1. Patients with a history for the last 2 years of other primary headache types, or secondary headache types except medication overuse headache 2. Patients with diagnosis of hemiplegic migraine or migrainous infarct 3. Patients with current regular use of Opioids, Cannabis, Medical Marijuana, etc 4. Women who are pregnant, lactating, or who are of childbearing age 5. Current involvement in an investigational (drug, device, etc.) clinical trial that may confound study endpoints. Participants in observational, natural history, and/or epidemiological studies not involving intervention are eligible. Sponsor approval is required

Primary outcome measure(s)

Trial sites (7)

FacilityCityRegionStatus
John Muir Physician Network Clin. Research Center Walnut Creek California Recruiting
Hartford Hospital Hartford Connecticut Recruiting
Mount Sinai New York New York Recruiting
Stony Brook University Medical Center Stony Brook New York Recruiting
Thomas Jefferson University Hospital Philadelphia Pennsylvania Recruiting
Semmes Murphey Foundation Memphis Tennessee Recruiting
West Virginia University Morgantown West Virginia Recruiting

Other trials for the same condition

Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT06735833 on ClinicalTrials.gov ↗ ← All trials in the USA