Clinical Trials in the USA / NCT06696443
Active, not recruiting
Phase 3
Evaluation of the Long-term Safety and Effectiveness of Suzetrigine (SUZ) in Participants With Painful Diabetic Peripheral Neuropathy (DPN)
NCT06696443 · tracked via the Priya Life Science USA tracker
Condition(s) studied
Diabetic Peripheral Neuropathic Pain
Investigational drug(s) / intervention(s)
Suzetrigine: Tablets for oral administration.
Study summary
The purpose of this study is to evaluate the long-term safety and tolerability of SUZ and long-term effectiveness of SUZ in treating pain associated with DPN.
Eligibility
Key Inclusion Criteria:
• Completed the final visit in the Treatment Period (i.e., Week 12) and subsequent 7-day period (to allow for taper of blinded capsule study drug) in a parent study such as VX24-548-110 or VX24-548-111
Key Exclusion Criteria:
* Any sensory abnormality (excluding DPN)
* History of drug intolerance in a parent study that would pose an additional risk to the participant in the opinion of the investigator
* Current participation in an investigational drug trial (other than a parent study)
Other protocol defined Inclusion/Exclusion criteria may apply.
Primary outcome measure(s)
- Safety and Tolerability as Assessed by Number of Participants With Adverse Events (AEs) and Serious Adverse Events (SAEs) — From Baseline up to Week 54
Trial sites (65)
| Facility | City | Region | Status |
|---|---|---|---|
| Pinnacle Research Group, LLC | Anniston | Alabama | |
| AMR Daphne, AL | Daphne | Alabama | |
| Scottsdale Clinical Trials | Scottsdale | Arizona | |
| Neuro-Pain Medical Center | Fresno | California | |
| Long Beach Research Institute | Long Beach | California | |
| Angel City Research, Inc | Los Angeles | California | |
| Empire Clinical Research | Pomona | California | |
| Clinical Trials Research | Sacramento | California | |
| Velocity Clinical Research, San Bernardino | San Bernardino | California | |
| SCLA Management - Pain Management and Injury Relief | Thousand Oaks | California | |
| Velocity Clinical Research - Denver | Englewood | Colorado | |
| Velocity Clinical Research - Washington DC | Washington D.C. | District of Columbia | |
| AMR-Miami | Coral Gables | Florida | |
| Accel Research - Deland | DeLand | Florida | |
| Suncoast Research Associates - Miami | Doral | Florida | |
| AMR Fort Myers (The Clinical Study Center) | Fort Myers | Florida | |
| Velocity Clinical Research - Hallandale Beach | Hallandale | Florida | |
| CNS Healthcare - Jacksonville | Jacksonville | Florida | |
| Accel Research Site - St. Petersburg/Largo | Largo | Florida | |
| Accel Research Sites - Maitland | Maitland | Florida | |
| 3Sync Research - Miami Lakes | Miami Lakes | Florida | |
| Suncoast Clinical Research - New Port Richey | New Port Richey | Florida | |
| Conquest Clinical Research - Orlando - Neuro | Orlando | Florida | |
| Conquest Clinical Research - Winter Park | Winter Park | Florida | |
| Accel Research - Decatur | Decatur | Georgia | |
| Velocity Clinical Research - Boise | Meridian | Idaho | |
| Feinberg School of Medicine - Anesthesiology | Chicago | Illinois | |
| Healthcare Research Network - Flossmoor IL | Tinley Park | Illinois | |
| Synexus Clinical Research - Evansville | Evansville | Indiana | |
| AMR Wichita East, KS (Heartland Research Associates) | Wichita | Kansas | |
| AMR Lexington | Lexington | Kentucky | |
| Velocity Clinical Research - Baton Rouge | Baton Rouge | Louisiana | |
| Tandem Clinical Research- Covington | Covington | Louisiana | |
| Mass General Brigham - Brigham and Women's Hospital - Main Campus | Boston | Massachusetts | |
| MedVadis Research Corporation | Waltham | Massachusetts | |
| Healthcare Research Network - Hazelwood MO | Hazelwood | Missouri | |
| AMR Kansas City | Kansas City | Missouri | |
| Velocity Clinical Research - Norfolk | Norfolk | Nebraska | |
| HRI - Hassman Research Institute | Marlton | New Jersey | |
| Velocity Clinical Research - Albuquerque | Albuquerque | New Mexico |
+ 25 more sites — see the full list on the official registry below.
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Official registry record
This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.
View NCT06696443 on ClinicalTrials.gov ↗ ← All trials in the USA