The purpose of this study is to characterize and assess the evolution of hearing impairment of patients with adulthood-onset bilateral sensorineural hearing loss carrying mutations on GJB2 gene.
Eligibility
Sex
ALL
Min age
30 Years
Max age
55 Years
Healthy volunteers
No
Inclusion Criteria:
1. Female or Male patients ≥30 and ≤55 years old
2. Bilateral hearing loss first noticed after the age of 16 years old
3. Documented genotyping results showing mutations in GJB2 gene.
Exclusion Criteria:
1. Deafness with a known, non-genetic cause
2. To the opinion of the investigator, unable and/or unwilling to comply with all the protocol requirements and/or study procedures
Primary outcome measure(s)
Evolution of hearing impairment of adult patients with early-onset presbycusis carrying mutations in GJB2 gene. — 2 years Evolution of hearing impairment assessed by Pure Tone Audiometry
Evolution of hearing impairment of adult patients with early-onset presbycusis carrying mutations in GJB2 gene — 2 years Evolution of hearing impairment assessed by Speech in noise
This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.
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