Perform® Humeral System - Fracture Study (PFX)

Inclusion Criteria: * 18 years or older at the time of the informed consent or the non-opposition (when applicable) * Informed and willing to sign an informed consent form (ICF) approved by IRB or EC (when applicable) * Willing and able to comply with the requirements of the study protocol * Considered a candidate for shoulder arthroplasty with the device for shoulder joint disabled by: * Traumatic or pathologic conditions of the shoulder resulting in fracture of the glenohumeral joint, including humeral head fracture and displaced 3-or 4-part proximal humeral fractures * Fracture sequelae * Revisions where adequate fixation can be achieved, and adequate bone stock remains after final reconstruction * Proximal humerus bone defect (reverse configuration) Exclusion Criteria: * Not able to comply with the study procedures based on the judgment of the assessor (e.g., cannot comprehend study questions, inability to keep scheduled assessment times) * Patient belongs to a vulnerable group of subjects, including minor subjects, those unable to decide for themselves to participate or needing a LAR, or others who could be subject to coercion (subjects who may not be acting on their own initiative) (referred as "vulnerable subject" in the section 3.44 of the ISO 14155:2011 norm) * Any absolute contraindications as mentioned in the device Instruction For Use (available on ifu.stryker.com)