🇮🇪Ireland
16°C Partly Cloudy · Dublin
Live Updates
--:--:-- IST
Writer Login
Latest
Clinical Trials in the UK / NCT06947993
Recruiting Phase 2

Platform Study to Evaluate the Efficacy and Safety of Investigational Compound(s) in Patients With Moderate to Severe Atopic Dermatitis

NCT06947993 · tracked via the Priya Life Science UK tracker
Sponsor
Novartis Pharmaceuticals
Phase
Phase 2
Started
2025-05-16
Last updated
2026-08-19

Condition(s) studied

Atopic Dermatitis

Investigational drug(s) / intervention(s)

GHZ339Placebo

GHZ339: GHZ339 administered at dose A, B, C and D

Placebo: Matching placebo

Study summary

This trial is designed to evaluate multiple compounds in participants with moderate to severe atopic dermatitis (AD).

Eligibility

Sex
ALL
Min age
18 Years
Max age
100 Years
Healthy volunteers
No
Key Inclusion Criteria of the master protocol: * Able and willing to sign the informed consent (IC) * Patients with a diagnosis of AD and onset of disease for at least 1 year * Moderate to severe AD Key Exclusion Criteria of the master protocol: * Participants with a clinically significant medical condition or infectious disease (specified in sub-protocol) * Participants with clinically significant abnormal hematology, clinical chemistry, or urine test results or clinically significant abnormal ECG * Participant with any other active inflammatory skin disease * Participants with any chronic, uncontrolled medical condition, which would put the participant at increased risk during the study (e.g., uncontrolled: diabetes, hypertension) * Participants with any clinically unstable disease states that would likely require systemic corticosteroids (e.g., uncontrolled asthma) Additional inclusion and exclusion criteria may apply depending on the intervention specific requirements

Primary outcome measure(s)

Trial sites (105)

FacilityCityRegionStatus
Novartis Investigative Site Birmingham Alabama Recruiting
Novartis Investigative Site Birmingham Alabama Recruiting
Novartis Investigative Site Fort Smith Arkansas Recruiting
Novartis Investigative Site Fountain Valley California Recruiting
Novartis Investigative Site Los Angeles California Recruiting
Novartis Investigative Site Sacramento California Recruiting
Novartis Investigative Site Santa Ana California Recruiting
Novartis Investigative Site Santa Monica California Recruiting
Novartis Investigative Site Washington D.C. District of Columbia Recruiting
Novartis Investigative Site Miami Florida Recruiting
Novartis Investigative Site St. Petersburg Florida Recruiting
Novartis Investigative Site Atlanta Georgia Recruiting
Novartis Investigative Site Macon Georgia Recruiting
Novartis Investigative Site Louisville Kentucky Recruiting
Novartis Investigative Site Brighton Massachusetts Recruiting
Novartis Investigative Site Troy Michigan Recruiting
Novartis Investigative Site Saint Joseph Missouri Recruiting
Novartis Investigative Site Portsmouth New Hampshire Recruiting
Novartis Investigative Site Brooklyn New York Recruiting
Novartis Investigative Site Arlington Texas Recruiting
Novartis Investigative Site Cypress Texas Recruiting
Novartis Investigative Site Dallas Texas Recruiting
Novartis Investigative Site Houston Texas Recruiting
Novartis Investigative Site San Antonio Texas Recruiting
Novartis Investigative Site Caba Buenos Aires Recruiting
Novartis Investigative Site Caba Buenos Aires Recruiting
Novartis Investigative Site Rosario Santa Fe Province Recruiting
Novartis Investigative Site Edmonton Alberta Active Not Recruiting
Novartis Investigative Site Hamilton Ontario Recruiting
Novartis Investigative Site Markham Ontario Recruiting
Novartis Investigative Site Montreal Quebec Recruiting
Novartis Investigative Site Verdun Quebec Active Not Recruiting
Novartis Investigative Site Guangzhou Guangdong Active Not Recruiting
Novartis Investigative Site Shantou Guangdong Active Not Recruiting
Novartis Investigative Site Changsha Hunan Active Not Recruiting
Novartis Investigative Site Changchun Jilin Active Not Recruiting
Novartis Investigative Site Hangzhou Zhejiang Recruiting
Novartis Investigative Site Beijing China Withdrawn
Novartis Investigative Site Beijing China Active Not Recruiting
Novartis Investigative Site Shanghai China Recruiting

+ 65 more sites — see the full list on the official registry below.

More Novartis Pharmaceuticals trials in the UK

Other trials for the same condition

Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT06947993 on ClinicalTrials.gov ↗ ← All trials in the UK