Transvaginal Shear Wave Elastography: Measurement of ovarian stromal elasticity using transvaginal shear wave elastography alongside standard ultrasound evaluation of antral follicle count and ovarian volume
Study summary
This study aims to evaluate the relationship between ovarian stromal stiffness measured by transvaginal shear wave elastography (SWE) and conventional hormonal and ultrasonographic parameters of ovarian reserve. Reproductive-aged female patients will be evaluated to determine whether tissue elasticity provided by SWE correlates with ovarian function markers such as anti-Müllerian hormone (AMH), antral follicle count (AFC), and ovarian volume.
Eligibility
Sex
FEMALE
Min age
18 Years
Max age
45 Years
Healthy volunteers
Accepted
Inclusion Criteria:
* Female patients aged 18 to 45 years.
* Regular menstrual cycles (21-35 days) or irregular menstruel cycles (oligo-anovaltion)
* Normal pelvic anatomy on baseline ultrasound evaluation.
* Written informed consent to participate in the study.
Exclusion Criteria:
* History of prior ovarian or adnexal surgery.
* History of pelvic radiotherapy or chemotherapy.
* Presence of structural pelvic/ovarian pathology (e.g., endometrioma, ovarian cyst, dermoid cyst, active pelvic inflammatory disease).
* Use of hormonal contraceptives, ovulation induction agents, or hormone therapy within the last 3 months.
* Pregnancy or current lactation.
* Severe obesity or technical limitations preventing adequate transvaginal ultrasound and elastography imaging
Primary outcome measure(s)
Ovarian Stromal Elasticity Value — At the time of baseline ultrasound examination(Day 1) Measurement of ovarian stromal tissue stiffness/elasticity using transvaginal shear wave elastography, expressed in kilopascals (kPa) or velocity (m/s).
Trial sites (1)
Facility
City
Region
Status
University of Health Sciences Gazi Yaşargil Training and Research Hospital, Department of Obstetrics and Gynaecology
Diyarbakır
Turkey (Türkiye)
More Saglik Bilimleri Universitesi Gazi Yasargil Training and Research Hospital trials in Turkey
This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.
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