Ultrasound-Guided Piriformis Injection: Ultrasound-guided injection of 5 mL of 2% lidocaine into the piriformis muscle for diagnostic confirmation. A patient-reported pain reduction of 50% or more at 1 hour after injection will be considered confirmation of piriformis syndrome.
Study summary
Piriformis syndrome is a clinical condition characterized by buttock pain and/or sciatic-like symptoms, and its diagnosis remains challenging because there is no universally accepted diagnostic standard. This study aims to evaluate the diagnostic accuracy of commonly used diagnostic criteria and clinical tests for piriformis syndrome. Participants with suspected piriformis syndrome will undergo standardized physical examination and assessment of predefined diagnostic criteria. Ultrasound-guided injection of 5 mL of 2% lidocaine into the piriformis muscle will be used as the reference diagnostic procedure. A reduction of 50% or more in pain after injection will be considered confirmation of piriformis syndrome. The diagnostic performance of clinical tests and diagnostic criteria will be analyzed accordingly.
Eligibility
Sex
ALL
Min age
18 Years
Max age
75 Years
Healthy volunteers
No
Inclusion Criteria:
* Adults aged 18 to 75 years
* Presentation with gluteal pain
* Pain on palpation in the piriformis region
Exclusion Criteria:
* History of injection to the lumbar, hip, or gluteal region within the last 3 months,including steroid, hyaluronic acid, or similar injections
* History of hip surgery
* Presence of active inflammatory rheumatic disease, including rheumatoid arthritis, ankylosing spondylitis, polymyalgia rheumatica, vasculitis, or similar conditions
* Active skin or subcutaneous soft tissue infection in the gluteal region
* Use of anticoagulant therapy that may contraindicate injection
* Presence of a bleeding disorder
* Uncontrolled diabetes mellitus and/or hypertension
* History of neurological disease
* Pregnancy or lactation
* Presence of a psychiatric disorder
* Known allergy to the injection agents
* History of malignancy
Primary outcome measure(s)
Diagnostic accuracy of clinical tests and diagnostic criteria for piriformis syndrome — Same day; pain response assessed 1 hour after injection Diagnostic accuracy of predefined clinical tests and diagnostic criteria will be evaluated using pain response to ultrasound-guided piriformis injection as the reference standard. A positive reference standard result will be defined as a patient-reported reduction of 50% or more in pain at 1 hour after injection compared with pre-injection pain. Participants with a positive reference standard result will be classified as having piriformis syndrome for the diagnostic accuracy analysis.
Trial sites (1)
Facility
City
Region
Status
Istanbul University-Cerrahpasa, Cerrahpasa Medical Faculty
Istanbul
Turkey (Türkiye)
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This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.
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