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Clinical Trials in Turkey / NCT07267650
Starting soon Observational

iPACK Block vs. Periarticular Infiltration for TKA Pain Control

NCT07267650 · tracked via the Priya Life Science Turkey tracker
Sponsor
Turgutlu State Hospital
Phase
Observational
Started
2026-05-01
Last updated
2026-06-01

Condition(s) studied

Pain, PostoperativeOsteoarthritis, Knee / Osteoarthritis, Hip

Study summary

This study aims to retrospectively compare two different multimodal analgesic techniques for pain management after total knee arthroplasty (TKA). The primary purpose is to evaluate whether a combination of two specific nerve blocks administered by an anesthesiologist (Femoral Triangle Block + iPACK block) resulted in superior postoperative pain control compared to a hybrid combination of a nerve block and a local infiltration administered by the surgeon (FTB + Periarticular Infiltration \[PAI\]).

The hypothesis is that the FTB + iPACK combination is associated with a significant reduction in Numeric Rating Scale (NRS) pain scores with movement at 24 hours postoperatively. This is a retrospective, observational cohort study conducted at a single center, involving medical records of patients who underwent primary unilateral TKA. Data from patients who received either FTB + iPACK or FTB + PAI as part of their standard clinical care will be extracted and analyzed retrospectively.

Eligibility

Sex
ALL
Min age
18 Years
Max age
80 Years
Healthy volunteers
No
Inclusion Criteria: * American Society of Anesthesiologists (ASA) physical status II-III. * Scheduled for elective, primary, unilateral total knee arthroplasty for osteoarthritis. * Able to provide written informed consent. Exclusion Criteria: * Patient refusal to participate or contraindication to regional anesthesia. * Known allergy to any study medications (local anesthetics, NSAIDs, tramadol, morphine, paracetamol). * History of chronic opioid use (defined as daily use for \>3 months) * Pre-existing peripheral neuropathy in the operative limb. * Severe renal or hepatic insufficiency. * Cognitive impairment preventing the use of pain scales or questionnaires. * Revision or bilateral knee arthroplasty.

Primary outcome measure(s)

Trial sites (1)

FacilityCityRegionStatus
Turgutlu State Hospital+ Manisa Manisa

Other trials for the same condition

Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT07267650 on ClinicalTrials.gov ↗ ← All trials in Turkey