Real-world Prospective Study on the Use of Anti-CGRP Drugs in Migraine

NCT07159750 · tracked via the Priya Life Science Turkey tracker

Sponsor

Hospital Universitari Vall d'Hebron Research Institute

Phase

Observational

Started

2024-01-02

Last updated

2025-09-08

Condition(s) studied

MigraineEpisodic MigraineChronic Migraine, Headache

Investigational drug(s) / intervention(s)

CGRP antibody or gepant

CGRP antibody or gepant: Patients will start anti-CGRP or its receptor antibody or gepants

Study summary

The goal of this observational study is to evaluate clinical differences in patients who received preventive treatment with medication targeting calcitonin gene-related peptide (CGRP) or its receptor: monoclonal antibodies (erenumab, galcanezumab, fremanezumab, eptinezumab) or gepants (rimegepant, atogepant) during a 2-year period observation phase.

Eligibility

Sex

ALL

Min age

18 Years

Max age

—

Healthy volunteers

Inclusion Criteria: * Migraine diagnosis according to ICHD-III. * Prescription of erenumab, galcanezumab, fremanezumab, eptinezumab, atogepant or rimegepant according to prescriptor criteria and reimbursement criteria according to local regulations. * Signature of informed consent. Exclusion Criteria: * Presence of headache different from migraine. * Active severe psychiatric condition or cognitive impairment which may affect the ability to consent patient's participation in the study.

Primary outcome measure(s)

Change in Monthly Headache Days and Monthly Migraine Days — Through study completion, an average of 2 years

Trial sites (26)

Facility	City	Region	Status
University of Miami, Miller School of Medicine	Miami	Florida	Recruiting
FLENI	Buenos Aires	Argentina	Recruiting
Pontificia Universidad Católica de Chile	Santiago	Chile	Recruiting
Neuromedica	Medellín	Colombia	Recruiting
Special Hospital for Orthopedics and Rehabilitation "Martin Horvat" Rovinj-Rovigno	Rovinj	Croatia	Recruiting
Charité Universitätsmedizin Berlin	Berlin	Germany	Recruiting
LMU University Hospital	München	Germany	Recruiting
University of L'Aquila	L’Aquila	Italy	Recruiting
University of Modena and Reggio Emilia	Modena	Italy	Recruiting
National Neurological Institute C. Mondino Foundation	Pavia	Italy	Recruiting
IRCCS San Raffaele	Roma	Italy	Recruiting
Universiti Putra Malaysia	Serdang	Selangor	Recruiting
Neuroclinic Norway	Lillestrøm	Norway	Recruiting
Wrocław Medical University	Wroclaw	Poland	Recruiting
Hospital Santa Maria Lisbon	Lisbon	Portugal	Recruiting
Germans Trias i Pujol Hospital	Badalona	Barcelona	Recruiting
Vall d'Hebron University Hospital	Barcelona	Barcelona	Recruiting
Hospital Universitari de Bellvitge	L'Hospitalet de Llobregat	Barcelona	Recruiting
Fundació Sanitària Mollet	Mollet del Vallès	Barcelona	Not Yet Recruiting
Hospital de Viladecans	Viladecans	Barcelona	Recruiting
Hospital General Universitario de Albacete	Albacete	Spain	Recruiting
Fundación Jiménez Díaz	Madrid	Spain	Recruiting
Hospital Universitario Gregorio Marañón	Madrid	Spain	Recruiting
La Paz University Hospital	Madrid	Spain	Recruiting
Hospital Clínico Universitario Lozano Blesa	Zaragoza	Spain	Recruiting
Mersin University	Mersin	Turkey (Türkiye)	Recruiting

Other trials for the same condition

The Impact of Greater Occipital Nerve and Stellate Ganglion Block Treatments on Sleep in Chronic Headache Management Starting soon

Impact of GON PRF on Central Sensitization in Migraine Patients Active, not recruiting

"Personalized Physiotherapy for Migraine: Effects on Pain, Fatigue, and Physical Function" Starting soon

Comparision of the Analgesic Effects of Intravenous Ibuprofen and Tenoxicam in Acute Migraine Attack Active, not recruiting

A Study of Eptinezumab in Pediatric Participants With Episodic Migraine Recruiting

Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT07159750 on ClinicalTrials.gov ↗ ← All trials in Turkey