Preoperative Neutrophil-to-Lymphocyte Ratio (NLR)Postdural Puncture Headache
Investigational drug(s) / intervention(s)
PDPH
PDPH: Observational analysis of preoperative inflammatory markers (e.g., NLR, PLR, SIRI) in relation to PDPH development following spinal anesthesia.
Study summary
This study will aim to investigate whether systemic inflammatory markers-especially the neutrophil-to-lymphocyte ratio (NLR)-obtained from preoperative complete blood counts can predict the development of post-dural puncture headache (PDPH) in obstetric patients undergoing cesarean section under spinal anesthesia.
Eligibility
Sex
FEMALE
Min age
18 Years
Max age
—
Healthy volunteers
No
Inclusion Criteria:
* Women aged 18 years or older
* Underwent elective or emergency cesarean section under spinal anesthesia
* Had complete preoperative complete blood count (CBC) data available
* No known hematological or inflammatory disease
* No intraoperative complications recorded
* Medical records accessible for postoperative follow-up regarding PDPH symptoms
Exclusion Criteria:
* Age under 18
* Absence of preoperative complete blood count data
* Presence of hematologic malignancy, active infection, autoimmune disease, or immunosuppressive therapy
* Platelet count \<150,000/mm³ or INR \>1.5
* Incomplete or missing medical records
Primary outcome measure(s)
Postdural Puncture Headache (PDPH) incidence — Within 10 days postoperatively The occurrence of PDPH symptoms within 10 days following spinal anesthesia in obstetric patients, as documented in medical records.
This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.
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