CancerLeukemiaHodgkin LymphomaTesticular CancerOsteosarcomaEwing SarcomaBreast CancerCervical Cancer
Investigational drug(s) / intervention(s)
Blood sampling
Blood sampling: Study measurements will be performed twice and consist of blood withdrawal and physical examination (weight, height, waist-hip ratio, and blood pressure).
Study summary
Longitudinal cohort study; measurements before start of systemic therapy and one year later.
Eligibility
Sex
ALL
Min age
18 Years
Max age
39 Years
Healthy volunteers
No
Inclusion Criteria:
* Aged 18-39 years at cancer diagnosis
* Having a histologically and/or cytologically confirmed cancer diagnosis, including leukemia, (non-)Hodgkin lymphoma, testicular cancer, osteosarcoma, Ewing sarcoma, breast cancer, and cervical cancer.
* Scheduled to start systemic therapy with curative intent. Allowed treatments (concurrent or sequential) are: surgery, radiotherapy, chemotherapy, antibodies.
Exclusion Criteria:
* patients who are not able to understand the patient information letter and informed consent form
* patients who will be treated with immune checkpoint inhibitors or targeted therapy with inhibitors of angiogenesis
* patients who have been treated with systemic therapy or radiotherapy for a previous malignancy (exceptions: in situ carcinoma of the cervix or uterus and adequately treated basal and squamous cell carcinoma of the skin).
Primary outcome measure(s)
Change in senescence marker P16 — at baseline and 1 year after start systemic therapy determine change in senescence marker P16 between start of systemic therapy and one year later.
Trial sites (1)
Facility
City
Region
Status
University Medical Center Groningen
Groningen
Netherlands
Recruiting
More University Medical Center Groningen trials in the Netherlands
This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.
We use cookies to analyse site traffic and improve your experience. With your consent, we may also use cookies for advertising. You can change your choice at any time.