Non Vital TeethPersistent Symptomatic Apical Periodontitis
Investigational drug(s) / intervention(s)
Endodontic Micro-SurgeryEndodontic Micro-Surgery
Endodontic Micro-Surgery: Procedure/Surgery: Endodontic Micro-Surgery
Patients with non vital teeth with persistant symptomatic apical periodontitis with lesion size \>5 mm not responding to conventional endodontic treatment \& planned for apical surgery using conventional retrograde root end filling technique.
Endodontic Micro-Surgery: Patients with non vital teeth with persistant symptomatic apical periodontitis with lesion size \>5 mm not responding to conventional endodontic treatment \& planned for apical surgery using orthograde plug of 6-7 mm.
Study summary
To evaluate and compare the effect of orthograde and retrograde MTA root end filling on clinical, 2D and 3D radiographic success and quality of life after periapical surgery in posteriors- A Randomised Control Trial
Eligibility
Sex
ALL
Min age
18 Years
Max age
55 Years
Healthy volunteers
Accepted
Inclusion Criteria:
* Patients in which non-surgical retreatment is unfeasible (anatomical complexity, iatrogenic errors) or previously failed treatment in cases of persistent symptomatic apical periodontitis involving posteriors.
* Tooth with a peri-radicular lesion of endodontic origin (chronic apical periodontitis) or endo-perio origin with the size of lesion ≥5mm.
* Teeth with less than 10 degree root curvature.
* Patients between 18-55 years of age.
* No general medical contraindications for oral surgical procedures (ASA-1 according to the classification of the American Society of Anesthesiologists)
* Tooth with adequate final restoration without clinical evidence of coronal leakage.
* Good periodontal health condition at tooth level.
* Able to completely understand and sign an informed consent form.
Exclusion Criteria:
* • Patients with systemic diseases (diabetes mellitus, uncontrolled hypertension grade III, hepatic/renal disease, or systemic bleeding disorders) (Bharathi et al 2021).
* Patients on anticoagulant/ antiplatelet drugs.
* Fractured/perforated teeth.
* Presence of vertical root fracture.
* Pregnancy.
Primary outcome measure(s)
Periapical healing assessment — Base line to 12 months Periapical healing comparison in 2 groups with 2d healing using Rud and Molven et al. (1987) score 1 is for Complete healing, score 2 for Incomplete healing (scar tissue), score3: Uncertain healing and score 4: Unsatisfactory healing (failure) 3d healing outcome will be measured by modified PENN 3D criteria which has score 1 for Complete healing, score 2:Limited healing, score 3:Uncertain healing and score4:Unsatisfactory healing.
Trial sites (1)
Facility
City
Region
Status
PGIDS
Rohtak
Haryana
Recruiting
More Postgraduate Institute of Dental Sciences Rohtak trials in India
This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.
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