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Clinical Trials in India / NCT07179835
Starting soon Not applicable

To Evaluate Periapical Healing Post Full Pulpotomy in Teeth With and Without Apical Periodontitis

NCT07179835 · tracked via the Priya Life Science India tracker
Sponsor
Postgraduate Institute of Dental Sciences Rohtak
Phase
Not applicable
Started
2025-10-15
Last updated
2025-09-18

Condition(s) studied

Apical Periodontitis

Investigational drug(s) / intervention(s)

Full pulpotomy in adults ≥18 years with restorable mandibular first or second molars diagnosed with irreversible pulpitis, with or without apical periodontitis.

Full pulpotomy in adults ≥18 years with restorable mandibular first or second molars diagnosed with irreversible pulpitis, with or without apical periodontitis.: Comparison of full pulpotomy with MTA in teeth with and without apical periodontitis

Study summary

This clinical study aims to evaluate the periapical and clinical healing outcomes of full pulpotomy using MTA in mandibular permanent molars diagnosed with symptomatic irreversible pulpitis. Patients will be stratified based on the presence or absence of apical periodontitis. Clinical and radiographic assessments will be conducted at baseline, 6 months, and 12 months to compare healing outcomes between groups. The study seeks to determine the effectiveness of full pulpotomy as a less invasive alternative to root canal treatment, even in teeth with apical pathosis.

Eligibility

Sex
ALL
Min age
18 Years
Max age
65 Years
Healthy volunteers
No
Inclusion Criteria: 1. The patient should be ≥18 years of age. 2. Restorable mature permanent 1st and 2nd Mandibular molars with extremely deep caries (≥2/3 dentine involvement) 3. Tooth should give positive response to pulp sensibility testing. 4. Radiographic finding of periapical index (PAI) score \>/=3 (for test group) , score \</= 2 (for control group) Exclusion criteria 1. Teeth with immature roots. 2. No pulp exposure after caries excavation. 3. Bleeding could not be controlled in 10 minutes. 4. Signs of pulpal necrosis, sinus tract, swelling, insufficient bleeding after pulp exposure. 5. History of analgesic intake in previous 1 week, or antibiotic intake in 1 month. 6. Internal/external resorption. 7. Contributory medical history (alcoholism, smokers, diabetic, hypertension, drug dependency, Heart or valve disease, hepatitis, herpes, immunodeficiency (HIV), infectious diseases, kidney or liver, migraine)

Primary outcome measure(s)

Trial sites (1)

FacilityCityRegionStatus
PGIDS, Rohtak Rohtak Haryana

More Postgraduate Institute of Dental Sciences Rohtak trials in India

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Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT07179835 on ClinicalTrials.gov ↗ ← All trials in India