SafeBoosC-IIIv - Does Cerebral Oximetry Monitoring Affect Renal Outcomes

Condition(s) studied

Investigational drug(s) / intervention(s)

Intervention Arm- Cerebral Oximetry + Treatment Guideline: if the cerebral oximeter shows low values, a pre designed treatment guideline will be followed and corrective actions taken.

Study summary

Cerebral oximetry monitoring allows clinicians to optimize blood flow to the brain and oxygenation using the SafeBoosC treatment guideline. The guideline's interventions aims to stabilize blood pressure and oxygen levels.

As low blood pressure is a risk factor for the development of kidney injury, normalizing blood pressure may decrease the incidence of kidney injury in new-borns who are on ventilator.

Eligibility

Primary outcome measure(s)

• composite outcome of death and acute kidney injury — From randomization to discharge up to 2months of life
  composite outcome of death and acute kidney injury

Trial sites (1)

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