A Stratified, Multi-ARm, muLti-site Randomised Platform Trial Aiming to Reduce the INcidence of Post-operative SSI

Inclusion Criteria: * Patients with at least one abdominal incision that is ≥5cm (open or laparoscopic extraction site), with an anticipated clean-contaminated, contaminated, or dirty surgical wound. Definitions and examples of contamination are given in Table 1. * Patients undergoing emergency (surgery on an unplanned admission) or elective (surgery on a planned admission) operations. * Any operative indication for abdominal surgery (excluding caesarean section; see exclusion criteria). * Patient able and willing to provide written informed consent (signature or a fingerprint) prior to surgery (including emergency cases). * Patients aged 5 years and over. (This criteria MUST be made country-specific. Each country will decide the lower (and upper, if applicable according to local regulations age limit for the trial. This will be dependent on country-specific regulatory approvals. Age eligibility will vary by country.) Exclusion Criteria: * Patient unable to complete post-operative follow-up (i.e., will not be contactable after discharge). * Patients undergoing clean surgical procedures. * Patients undergoing an obstetrics procedure, including caesarean sections.