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Clinical trial register · European Union · CTIS

Recently authorised EU trials

The most recently authorised trials on the EU Clinical Trials Information System (CTIS), the single register for every trial run under the EU Clinical Trials Regulation (536/2014). CTIS holds a far larger historical archive than any one list can usefully show — this register states both numbers rather than picking one.

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Source: EMA Clinical Trials Information System (CTIS). Showing the 2500 most recently authorised of 12445 total CTIS records — a stated recency window, not the full historical archive. Synced 21 Sep 2026, 03:16 UTC
2500
Shown in this register
most recently authorised
12,445
Total on CTIS
full historical archive
745
Phase III
within the shown window
Top member states
Spain 1023 France 890 Germany 861 Italy 742 Poland 587 Netherlands 524
Narrow the registerReset
Phase
Phase I 558 Phase I/II 214 Phase II 726 Phase III 745 Phase IV 257
Lead sponsor
AstraZeneca AB 60 Assistance Publique Hopitaux De Paris 49 Merck Sharp & Dohme LLC 48 Pfizer Inc. 45 Novo Nordisk A/S 42
Member state
Spain 1023 France 890 Germany 861 Italy 742 Poland 587 Netherlands 524 Belgium 426 Czechia 327
All 28 states
257 of 2500 shown studies
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Phase
Study
Lead sponsor
Area
Member states
Decision
Phase IV
CANIDIAP; CANagliflozin In DIAlysis Patients
2025-522742-46-00Chronic Kidney disease
Universitair Medisch Centrum Groningen
Not possible to specify
Netherlands
23/02/2026
Phase IV
Efficacy and tolerability of a simethicone-containing evacuating solution for colorectal cancer screening colonoscopy: a randomized parallel comparative trial. CLEAN+
2025-523748-11-00colorectal cancer early detection
Fundacio De Recerca Clinic Barcelona-Institut D’Investigacions Biomediques August Pi I Sunyer
Digestive System Diseases
Spain
20/02/2026
Phase IV
Two initial aflibercept 8 mg loading doses in treatment-naive neovascular AMD
2025-523478-17-00Neovascular age-related macular degeneration
Medical University Of Graz
Eye Diseases
Austria
16/02/2026
Phase IV
Changes in the wound microbiome and their impact on chronic wound healing under hyperbaric conditions
2025-523863-39-00chronic wounds
Medical University Of Graz
Skin and Connective Tissue Diseases
Austria
16/02/2026
Phase IV
A randomized, placebo controlled, observer-blind, phase IV pragmatic trial to evaluate the effect of Recombinant Zoster Vaccine (Shingrix®) on incident dementia diagnosis in an older adult population aged ≥76 years in Finland
2025-524598-17-00Incident dementia
GlaxoSmithKline Biologicals
Nervous System Diseases
Finland
16/02/2026
Phase IV
An interventional, Open-label Study to Evaluate the effect of lebrikizumab on eczema and Skin Barrier Function parameters in lesional and non-lesional skin in Adults and Adolescents with Moderate to Severe Atopic Dermatitis
2024-519811-32-00Atopic dermatitis
Region Oestergoetland
Skin and Connective Tissue Diseases
Sweden
12/02/2026
Phase IV
Long-term Safety Outcomes in Patients Treated With Replimune Oncolytic Immunotherapy Products
2025-521621-33-00Hepatocellular Carcinoma, Melanoma, Metastatic Melanoma, Ad…
Replimune Group Inc.
Neoplasms
Germany, Greece, France, Poland, Spain
09/02/2026
Phase IV
Caffeine Administration for Preterms: Pharmacokinetics, Utilization and Correlation Inhibiting Nociception Outcome
2025-523475-33-00Primary apnea in preterms newborns
Masarykova Univerzita
Congenital, Hereditary, and Neonatal Diseases and Abnormalities
Czechia
09/02/2026
Phase IV
(23026) A prospective, single-arm, Phase 4 study to evaluate the course of serum transthyretin (TTR) level with acoramidis in adult patients with variant or wild-type transthyretin amyloidosis with cardiomyopathy (ATTR-CM) previously treated with tafamidis.
2025-521831-35-00Transthyretin Amyloid Cardiomyopathy (ATTR-CM)
Bayer Consumer Care AG
Cardiovascular Diseases
Austria, Germany, Italy, Belgium
07/02/2026
Phase IV
The effect of anifrolumab on cutaneous lupus erythematosus characterized by the change of the inflammatory infiltrate analyzed by immunohistochemistry, spatial transcriptomics and single-cell RNA- and TCR-sequencing as well as on the clinical outcome - an open label, single arm phase IV pilot study
2025-523133-26-00cutaneous lupus erythematosus
Medical University Of Vienna
Skin and Connective Tissue Diseases
Austria
07/02/2026
Phase IV
Rapid Oral Switch in Infectious Endocarditis, the ROSIE trial
2025-524484-20-00Infective Endocarditis
UZ Leuven
Bacterial Infections and Mycoses
Belgium
06/02/2026
Phase IV
A Randomized, Non-inferiority Trial Comparing 7-Day Versus 4-Week Esomeprazole Treatment in Patients with Unexplained Dyspepsia
2025-524044-35-00Dyspepsia
Landspitali
Digestive System Diseases
Iceland
06/02/2026
Phase IV
Adductor canal and IPACK (infiltration between the popliteal artery and the capsule of the knee) blocks versus genicular nerves block for total knee arthroplasty: A randomized clinical trial
2025-523071-34-00Knee Osteoarthritis
Fundacio De Recerca Clinic Barcelona-Institut D’Investigacions Biomediques August Pi I Sunyer
Musculoskeletal Diseases
Spain
06/02/2026
Phase IV
Efficacy of MIrikizumab to achieve traNsmural healing in patiENTs with Crohn’s Disease : EMINENT CD
2025-521889-95-00Crohn's Disease
Groupe D'etude Therapeutique Des Affections Inflammatoires Du Tube Digestif
Digestive System Diseases
France
05/02/2026
Phase IV
Changes in Coronary Plaque Composition By Semaglutide Use in Diabetic Patients With Acute Coronary Syndrome: A Randomized Optical Coherence Tomography Trial - ARMYDA - 10 study
2025-523977-40-00non-ST-elevation myocardial infarction (NSTEMI); unstable a…
Azienda Ospedaliero-Universitaria Maggiore Della Carita
Cardiovascular Diseases
Italy
28/01/2026
Phase IV
Tailored antiplatelet secondary prevention in non-cardioembolic ischemic stroke: a phase IV gender-stratified randomized controlled trial (TAILOR trial)
2025-523065-16-00Non-cardioembolic ischemic stroke
Azienda Unita Sanitaria Locale Di Bologna
Cardiovascular Diseases
Italy
28/01/2026
Phase IV
Multicentre, open-label, randomized controlled non-inferiority trial comparing single dose intrathecal morphine and continuous thoracic epidural analgesia for multimodal analgesia in open colorectal surgery: the ColoREDIT protocol
2024-520262-58-01All diseases requiring resective colorectal surgery with a …
Region Vaestmanland
Anesthesia and Analgesia
Sweden
28/01/2026
Phase IV
EFFICACY OF INFILTRATED MEPIVACAINE AS A LOCAL ANESTHETIC PRIOR TO ARTERIAL PUNCTURE: A RANDOMIZED CONTROLLED CLINICAL TRIAL
2025-522974-35-00Respiratory disease. Prescripcion o indicación de gasometrí…
University Of The Basque Country
Respiratory Tract Diseases
Spain
28/01/2026
Phase IV
The efficacy of pipamperone and aripiprazole on behaviors that challenge in people with intellectual disabilities: A series of N-of-1 cross-over trials
2024-519833-51-00Behaviors that challenge
Stichting GGZ Drenthe
Behavioral Disciplines and Activities
Netherlands
28/01/2026
Phase IV
Exploring the Psychoactive Effects of Paracetamol: A parallel group, basic science, double blind, two armed study, to investigate potential emotional and cognitive effects of paracetamol (tablet form) compared to a placebo (tablet form) in healthy male and female participants between ages 18 and 30.
2025-522753-19-02Healthy adults aged 18-30.
Oslo Metropolitan University
Psychological Phenomena
Norway
27/01/2026
Phase IV
Intrathecal baclofen pump versus selective dorsal rhizotomy for non-ambulatory children with cerebral palsy
2024-518822-33-01Cerebral Palsy
UZ Leuven
Nervous System Diseases
Netherlands, Belgium
27/01/2026
Phase IV
Early Lyophilised plasma In Patients with haemorrhagic Shock (ELIPS-Trial)
2025-523151-66-00Haemorrhagic shock
Johannes Kepler University Linz
Anesthesia and Analgesia
Austria
26/01/2026
Phase IV
Morphine PCA vs Morphine and Lidocaine PCA for the treatment of vaso-occlusive crisis-related pain in sickle-cell anaemia patients: a prospective, randomized, double blind monocentric trial.
2025-523777-41-01sickle cell anaemia
CHU Saint Pierre
Congenital, Hereditary, and Neonatal Diseases and Abnormalities
Belgium
26/01/2026
Phase IV
A multicenter, prospective clinical TRrial evaluating patient’s ability to make an independent and safe decision regarding the USe of the medicinal product Sildenafil Polpharma100 mg indicated in the Treatment of erectile dysfunction. TRUST Trial on Responsible Use and Self-assessed Treatment.
2025-522923-81-00Erectile dysfunction
ZAKLADY FARMACEUTYCZNE POLPHARMA S.A.
Male Urogenital Diseases
Poland
26/01/2026
Phase IV
The effect op corticosteroids on quality of life following total hip arthroplasty: HIPSTER study
2025-524368-39-00Patients aged 60 years or older undergoing total hip arthro…
Ziekenhuis Oost Limburg
Anesthesia and Analgesia
Belgium
21/01/2026
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Priya Life Science (2026). EU Clinical Trials Register (CTIS), filtered. Derived from the EMA Clinical Trials Information System. Retrieved 21 September 2026. https://priyalifescience.com/clinical-trials-europe

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Listing here is informational and not medical advice; eligibility is determined by each study team. Looking for Irish sites? See the Ireland, UK or USA registers. For approved medicines, see the EMA Approvals Tracker.