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Clinical trial register · European Union · CTIS

Recently authorised EU trials

The most recently authorised trials on the EU Clinical Trials Information System (CTIS), the single register for every trial run under the EU Clinical Trials Regulation (536/2014). CTIS holds a far larger historical archive than any one list can usefully show — this register states both numbers rather than picking one.

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Source: EMA Clinical Trials Information System (CTIS). Showing the 2500 most recently authorised of 12445 total CTIS records — a stated recency window, not the full historical archive. Synced 21 Sep 2026, 03:16 UTC
2500
Shown in this register
most recently authorised
12,445
Total on CTIS
full historical archive
745
Phase III
within the shown window
Top member states
Spain 1023 France 890 Germany 861 Italy 742 Poland 587 Netherlands 524
Narrow the registerReset
Phase
Phase I 558 Phase I/II 214 Phase II 726 Phase III 745 Phase IV 257
Lead sponsor
AstraZeneca AB 60 Assistance Publique Hopitaux De Paris 49 Merck Sharp & Dohme LLC 48 Pfizer Inc. 45 Novo Nordisk A/S 42
Member state
Spain 1023 France 890 Germany 861 Italy 742 Poland 587 Netherlands 524 Belgium 426 Czechia 327
All 28 states
257 of 2500 shown studies
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Phase
Study
Lead sponsor
Area
Member states
Decision
Phase IV
Evidence based empirical antibiotic treatment for urinary tract infections requiring hospitalisation - TRI-AB trial
2024-520251-24-00Complicated urinary tract infections (cUTI) requiring hospi…
Odense University Hospital
Bacterial Infections and Mycoses
Denmark
27/03/2026
Phase IV
Dexamethasone for the treatment of traumatic brain injured patients with brain contusions and pericontusional edema: Study protocol for a prospective, randomized and double blind trial
2025-520887-17-00Post-traumatic brain contusion with edema
University Hospital Son Espases
Nervous System Diseases
Spain
26/03/2026
Phase IV
Randomized, multicenter, open-label clinical trial to evaluate the clinical and microbiological impact of methenamine hippurate as an alternative prophylaxis to antibiotics in the management of recurrent urinary tract infections in women
2025-523922-42-00recurrent urine infections
Consorci Mar Parc De Salut De Barcelona
Female Urogenital Diseases and Pregnancy Complications
Spain
25/03/2026
Phase IV
Non-inferiority study of TOCILIZUMAB in dose-banding versus dose-weight in rheumatoid arthritis with low activity or clinical remission
2025-522319-41-00rheumatoid arthritis
Centre Hospitalier Universitaire De Nice
Musculoskeletal Diseases
France
24/03/2026
Phase IV
Fludarabine exposure in patients undergoing Fludarabine based lymphodepletion prior to CAR-T cell therapy
2025-524278-40-00Patients undergoing Fludarabine based lymphodepletion prior…
Universitair Ziekenhuis Gent
Hemic and Lymphatic Diseases
Belgium
23/03/2026
Phase IV
Direct comparison of Tezepelumab and Dupilumab in CRSwNP in a real world setting
2025-524495-39-00Chronic Rhinosinusitis with Nasal Polyps
Medical University Of Vienna
Otorhinolaryngologic Diseases
Austria
22/03/2026
Phase IV
GUselkumAb inteRvention and DIet evaluAtioN for pouchitis
2025-521683-35-00Pouchitis
UZ Leuven
Nutritional and Metabolic Diseases
Belgium
19/03/2026
Phase IV
Efficacy and safety of pharmacological therapy of obesity in liver transplant candidates
2026-526044-12-00Obesity
Institute For Clinical And Experimental Medicine
Digestive System Diseases
Czechia
18/03/2026
Phase IV
Use of half the iodinated contrast medium for monitoring thoracic neoplasms using spectral CT: Randomized, crossover, non-inferiority clinical trial
2025-524901-33-00Thoracic neoplasm
Fundacion De La Comunitat Valenciana Para La Gestion Del Instituto De Investigacion Sanitaria Y Biomedica De Alicante
Diagnosis
Spain
17/03/2026
Phase IV
Cholesterol lowering with atorvastatine for the prevention of gallstones following bariatric surgery (CHOLSTONE): an investigator- blinded randomised controlled trial
2025-524191-38-00Gallstones (chole(cysto)lithiasis) following bariatric surg…
Spaarne Gasthuis Stichting
Nutritional and Metabolic Diseases
Netherlands
17/03/2026
Phase IV
PREDICTION OF COMPLICATIONS IN PATIENTS UNDERGOING SURGICAL TREATMENT OF HEPATIC TUMORS
2025-524477-17-00Hepatic tumor, Hepatic tumor(s)
Rigshospitalet
Neoplasms
Denmark
17/03/2026
Phase IV
Evaluating the clinical effectiveness of sodium bicarbonate for critically ill patients with metabolic acidosis and acute kidney injury
2025-523914-10-00Critical illness, Acute kidney injury, Metabolic acidosis
Universitaet Muenster
Nutritional and Metabolic Diseases
Germany
17/03/2026
Phase IV
The POST-PRANDIAL HYPO-AVOID STUDY Low-Dose Glucagon and Automated Insulin Delivery for Prevention of Spontaneous Exercise-Induced Hypoglycemia in People with Type 1 Diabetes
2025-523996-45-00Type 1 Diabetes Mellitus
Steno Diabetes Center Copenhagen
Hormonal diseases
Denmark
16/03/2026
Phase IV
The effect of Broncho-Vaxom on the COPD exacerbations in terms of lung function, lung mechanics, immune state, body composition, quality of life and physical activity.
2025-524501-32-02COPD exacerbation
Semmelweis University, University Of Pecs
Respiratory Tract Diseases
Hungary
13/03/2026
Phase IV
Impact Of Upadacitinib On The Frequency Of Acute Recurrent Anterior Uveitis In Patients With Axial Spondyloarthritis (UP-FOR-U)
2025-522118-21-00Axial Spondyloarthritis, Acute Anterior Uveitis
Care Arthritis Ltd.
Eye Diseases
Spain, Poland, Netherlands, France, Bulgaria, Germany
13/03/2026
Phase IV
GASPS Study: General Anaesthesia vs Spinal anaesthesia: Patient outcomes and Success in Outpatient primary total knee and hip Arthroplasty
2024-520127-89-00Total knee and hip arthroplasties
Region Oerebro Laen
Surgical Procedures, Operative
Sweden
12/03/2026
Phase IV
ILHEP : Effect of perioperative Intravenous Lidocaine on postoperative opioid related-side effects after open HEPatectomy: a multicentre prospective randomized controlled study
2025-522462-73-00Postanesthetic complications in patients undergoing open he…
Centre Hospitalier Universitaire De Rennes
Anesthesia and Analgesia
France
10/03/2026
Phase IV
Luteal phase support following letrozole treatment in women undergoing intrauterine insemination: a multicenter randomized trial
2025-524327-53-00Infertility
Region Midtjylland
Not possible to specify
Denmark
09/03/2026
Phase IV
Botulinum toxin in open abdomen closure. A multicentric randomized controlled single-blind clinical trial to evaluate the efficacy of early administration of botulinum toxin for primary midline closure in patients with an open abdomen.
2025-522410-23-00open abdomen
Hospital Universitario La Paz
Not possible to specify
Spain
04/03/2026
Phase IV
Intrathecal drug delivery systems versus comprehensive medical management for severe cancer pain: a randomized controlled trial
2025-522381-68-00Severe refractory cancer pain
Vrije Universiteit Brussel
Anesthesia and Analgesia
Belgium
04/03/2026
Phase IV
A Pragmatic Randomized Trial to Evaluate the Effect of Recombinant Herpes Zoster Vaccine on Major Adverse Cardiovascular Events and Dementia in Adults Aged 65 Years or Above
2025-524944-37-00Herpes Zoster
Gentofte Hospital, GlaxoSmithKline Biologicals
Skin and Connective Tissue Diseases
Denmark
04/03/2026
Phase IV
Impact of Early Thyroid Hormone Replacement on Kidney Function and Health-Related Quality of Life in Patients at Risk of Postoperative Hypothyroidism after Hemithyroidectomy: A Randomised Controlled Trial
2025-524175-23-00Hypothyroidism, Incident Kidney Dysfunction, Chronic Kidney…
Region Midtjylland
Otorhinolaryngologic Diseases
Denmark
03/03/2026
Phase IV
A multicentre randomized double-blind placebo-controlled 48-week superiority study to compare the efficacy and safety of rituximab versus placebo in rheumatoid arthritis-associated interstitial lung disease - the BELLRA trial.
2025-524872-51-00Rheumatoid arthritis-associated interstitial lung disease (…
Vaestra Goetalandsregionen
Immune System Diseases
Sweden
27/02/2026
Phase IV
A multi-center, open label, longitudinal, observational, 12-week study of Flexilev treatment with the dosing device OraFID and accompanying digital app in Parkinson patients.
2025-524296-23-01Parkinsons Disease
Navamedic AB
Nervous System Diseases
Sweden
24/02/2026
Phase IV
Effect of Romosozumab vs. Denosumab on Coronary Atherosclerotic Damage in Postmenopausal Osteoporotic Women: A Phase IV, Low-Risk, Pharmacological Intervention Study. ATRIO Study.
2025-522592-29-00Coronary atherosclerotic status in women with postmenopausa…
Ospedale Galeazzi S.p.A.
Musculoskeletal Diseases
Italy
23/02/2026
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Priya Life Science (2026). EU Clinical Trials Register (CTIS), filtered. Derived from the EMA Clinical Trials Information System. Retrieved 21 September 2026. https://priyalifescience.com/clinical-trials-europe

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Listing here is informational and not medical advice; eligibility is determined by each study team. Looking for Irish sites? See the Ireland, UK or USA registers. For approved medicines, see the EMA Approvals Tracker.