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Clinical Trials in the EU / 2026-526087-20-00
Authorised Phase II

A Randomized, Double-Blind, Placebo-Controlled Dose-Ranging Study to Evaluate the Efficacy and Safety of Nalbuphine Extended-Release Tablets for the Treatment of Participants with Refractory Chronic Cough

2026-526087-20-00 · tracked via the Priya Life Science EU tracker
Sponsor
Trevi Therapeutics Inc.
Sponsor type
Pharmaceutical company
Therapeutic area
Respiratory Tract Diseases
Decision date
24/09/2026
Enrollment target
32
Sites
Poland

Condition studied

Refractory Chronic Cough

Investigational medicinal product(s)

Placebo to match Nalbuphine erNalbuphine ERNalbuphine ER

Eligibility

Age group
65+ years, 18-64 years
Sex
Female, Male

Primary endpoint

Relative change from baseline in 24-hour cough frequency at Week 6 for each dose of NAL ER compared with placebo.

Endpoint detail

Relative change from baseline in 24-hour cough frequency at prespecified timepoints for NAL ER compared with placebo.

Official registry record

This page summarises publicly available CTIS data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View 2026-526087-20-00 on CTIS ↗ ← All trials in the EU