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Clinical Trials in the EU / 2026-525213-31-00
Ongoing Phase II

A Phase 2 Open-Label, Umbrella Platform Design Study of Investigational Agent(s) in Participants With 2L/3L Unresectable Locally Advanced or Metastatic Esophageal Cancer: KEYMAKER-U06 Substudy 06F

2026-525213-31-00 · tracked via the Priya Life Science EU tracker
Sponsor
Merck Sharp & Dohme LLC
Sponsor type
Pharmaceutical company
Therapeutic area
Neoplasms
Decision date
12/05/2026
Enrollment target
12
Sites
Czechia, Germany, France, Norway

Condition studied

Esophageal squamous cell carcinoma

Investigational medicinal product(s)

Ifinatamab Deruxtecan

Eligibility

Age group
65+ years, 18-64 years
Sex
Female, Male

Primary endpoint

Objective response rate (ORR)

Endpoint detail

Duration of response (DOR), Progression-free survival (PFS), Overall survival (OS), Number of participants who experience an adverse event (AE), Number of participants who discontinue study intervention due to an AE

Official registry record

This page summarises publicly available CTIS data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View 2026-525213-31-00 on CTIS ↗ ← All trials in the EU