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Clinical Trials in the EU / 2025-525133-31-00
Authorised Phase III

A Phase 3b, Multicentre, Randomised, Double-Blind, Placebo-Controlled, Parallel-Group Study to Evaluate the Efficacy and Safety of Lebrikizumab in Adult and Adolescent Participants with Moderate-to-Severe Face and Neck Atopic Dermatitis

2025-525133-31-00 · tracked via the Priya Life Science EU tracker
Sponsor
Almirall S.A.
Sponsor type
Pharmaceutical company
Therapeutic area
Skin and Connective Tissue Diseases
Decision date
22/09/2026
Enrollment target
15
Sites
Denmark

Condition studied

Face and Neck Atopic Dermatitis

Investigational medicinal product(s)

Solution for injectioncontaining the same excipients as the respective active lebrikizumab. Identical in appearance to test IMP. Supplied as a sterile PFS NSD.Ebglyss 250 mg solution for injection in pre-filled syringe

Eligibility

Age group
65+ years, 18-64 years, 0-17 years
Sex
Female, Male

Primary endpoint

Percentage of participants achieving an IGA score of 0 or 1 and a reduction ≥2 points from Baseline at Week 16

Endpoint detail

1. Percentage of participants with DLQI ≥4 points at Baseline achieving DLQI ≥4-point improvement from Baseline at Week 16, 2. Percentage change from Baseline to Week 16 in SCORing AD (SCORAD)

Official registry record

This page summarises publicly available CTIS data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View 2025-525133-31-00 on CTIS ↗ ← All trials in the EU