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Clinical Trials in the EU / 2025-524894-17-00
Completed Phase III

A randomized double-masked, multicenter, 3-arm, pivotal Phase 2/3 study to evaluate the efficacy and safety of intravitreal (IVT) EYE201/MK-8748 compared to aflibercept (2 mg) in participants with neovascular age-related macular degeneration (NVAMD)

2025-524894-17-00 · tracked via the Priya Life Science EU tracker
Sponsor
Eyebiotech Limited
Sponsor type
Laboratory/Research/Testing facility
Therapeutic area
Eye Diseases
Decision date
05/06/2026
Enrollment target
250
Sites
Austria, Slovakia, Portugal, Czechia, Hungary, Spain, France, Denmark, Italy, Croatia

Condition studied

Neovascular age-related macular degeneration (NVAMD)

Investigational medicinal product(s)

FLUORESCEINAFLIBERCEPT

Eligibility

Age group
65+ years, 18-64 years
Sex
Female, Male

Primary endpoint

Mean change in best-corrected visual acuity (BCVA) (Early Treatment of Diabetic Retinopathy Study [ETDRS]) letter score from baseline to Year 1

Official registry record

This page summarises publicly available CTIS data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View 2025-524894-17-00 on CTIS ↗ ← All trials in the EU