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Clinical Trials in the EU / 2025-524435-39-00
Authorised Phase II

A randomized, double-blind, placebo-controlled study to evaluate the efficacy and safety of 250 mg lebrikizumab in patients with localized scleroderma (LEMO)

2025-524435-39-00 · tracked via the Priya Life Science EU tracker
Sponsor
Charite Universitaetsmedizin Berlin KöR
Sponsor type
Hospital/Clinic/Other health care facility
Therapeutic area
Skin and Connective Tissue Diseases
Decision date
08/05/2026
Enrollment target
78
Sites
Germany

Condition studied

Localized Scleroderma

Investigational medicinal product(s)

Matching placebo to IMPEbglyss 250 mg solution for injection in pre-filled syringe

Eligibility

Age group
18-64 years, 65+ years
Sex
Female, Male

Primary endpoint

mLoSSI score after 24 weeks. Absolute change from baseline visit in mLoSSI score will be compared between groups

Official registry record

This page summarises publicly available CTIS data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View 2025-524435-39-00 on CTIS ↗ ← All trials in the EU