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Clinical Trials in the EU / 2025-523935-20-00
Ongoing Phase III

A Randomized, Double-blind, Parallel-group Phase III Study to Evaluate the Efficacy, Safety, and Tolerability of Elecoglipron Compared with Placebo in Adults with Type 2 Diabetes Mellitus on Background Insulin (Eluminate-3)

2025-523935-20-00 · tracked via the Priya Life Science EU tracker
Sponsor
AstraZeneca AB
Sponsor type
Pharmaceutical company
Therapeutic area
Nutritional and Metabolic Diseases
Decision date
04/08/2026
Enrollment target
200
Sites
Poland, Germany, Bulgaria, Czechia

Condition studied

type 2 diabetes mellitus

Investigational medicinal product(s)

ElecoglipronPlacebo for Elecoglipron (AZD5004)ElecoglipronElecoglipronElecoglipron

Eligibility

Age group
18-64 years, 65+ years
Sex
Female, Male

Primary endpoint

Change from baseline to Week 40 in HbA1c (%)

Endpoint detail

Achieved HbA1c < 7% (53 mmol/mol) at Week 40, Achieved HbA1c ≤ 6.5% (48 mmol/mol) at Week 40, Percent change from baseline to Week 40 in body weight, Change from baseline to Week 40 in body weight (kg), Change from baseline to Week 40 in SBP

Official registry record

This page summarises publicly available CTIS data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View 2025-523935-20-00 on CTIS ↗ ← All trials in the EU