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Clinical Trials in the EU / 2025-523283-21-00
Completed Phase III

J2A-MC-GZPR: A Study to Investigate the Efficacy and Safety of Orforglipron Once Daily in Participants with Peripheral Artery Disease: A Randomized, Double-Blind, Placebo Controlled Trial

2025-523283-21-00 · tracked via the Priya Life Science EU tracker
Sponsor
Eli Lilly & Co.
Sponsor type
Pharmaceutical company
Therapeutic area
Cardiovascular Diseases
Decision date
17/02/2026
Enrollment target
185
Sites
Slovakia, Poland, France, Netherlands

Condition studied

Peripheral Arterial Disease

Investigational medicinal product(s)

OrforglipronOrforglipronOrforglipronOrforglipronOrforglipronPlacebo to match lyOrforglipron

Eligibility

Age group
18-64 years, 65+ years
Sex
Female, Male

Primary endpoint

Percent Change from Baseline in Maximum Walking Distance On a constant load treadmill test [Time Frame: Baseline, Week 52]

Official registry record

This page summarises publicly available CTIS data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View 2025-523283-21-00 on CTIS ↗ ← All trials in the EU