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Clinical Trials in the EU / 2025-522585-72-00
Completed Phase IV

Efficacy of top-down therapy with mirikizumab versus standard of care with azathioprine in patients with newly diagnosed moderate-to-severe ulcerative colitis: A 52-week, multicenter, open-label, randomized controlled trial

2025-522585-72-00 · tracked via the Priya Life Science EU tracker
Sponsor
Universitaetsklinikum Schleswig-Holstein AöR
Sponsor type
Hospital/Clinic/Other health care facility
Therapeutic area
Digestive System Diseases
Decision date
26/09/2025
Enrollment target
300
Sites
Germany

Condition studied

ulcerative colitis

Investigational medicinal product(s)

MIRIKIZUMAB-AZATHIOPRINEMIRIKIZUMAB

Eligibility

Age group
18-64 years, 65+ years
Sex
Female, Male

Primary endpoint

The proportion of patients achieving comprehensive disease control at Week 52.

Official registry record

This page summarises publicly available CTIS data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View 2025-522585-72-00 on CTIS ↗ ← All trials in the EU