Long-term muscle synthetic effects of intradialytic parenteral nutrition in chronic hemodialysis patients

Condition studied

muscle protein turnover hemodialysis

Investigational medicinal product(s)

Eligibility

Primary endpoint

Difference in myofibrillar fractional synthetic rate during a one-week treatment with IDPN versus control

Endpoint detail

1. Intradialytic forearm amino acid balance, 2. difference in the loss of amino acids in the dialysate during a one-week treatment with IDPN versus control period, 3. Effects of IDPN on intradialytic blood pressure and cardiac output.