A Phase 3, Randomized, Double-blind, Placebo-controlled, Study to Evaluate the Efficacy and Safety of Adjunctive KarXT for the Treatment of Mania, With or Without Mixed Features, in Individuals with Bipolar-I Disorder Taking Lithium, Valproate, or Lamotrigine
Change from baseline in Young Mania Rating Scale (YMRS, used to evaluate manic symptoms) score at Week 5.
Endpoint detail
Change from baseline in CGI-BP (used to evaluate daily functioning) at Week 5.
Official registry record
This page summarises publicly available CTIS data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.
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