Antidepressant effects of psilocybin in the absence of serotoninergic psychedelic experience: a dimensional functional neuroimaging approach

Condition studied

Major depressive disorder

Investigational medicinal product(s)

Eligibility

Primary endpoint

Brain connectivity assessments using MRI: A resting-state functional sequence. A T1-weighted anatomical sequence. Using a brain rsNFC study model, beta measurement values will be obtained from the images. Statistically significant changes in these beta measures will be considered relevant to the study results.