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Clinical Trials in the EU / 2025-521416-19-00
Completed Phase II

A Phase IIb, Randomized, Double-blind, Placebo-controlled Study to Evaluate the Efficacy and Safety of AZD5148 for Prevention of Recurrence of Clostridioides difficile Infection in Individuals 18 Years of Age and Above

2025-521416-19-00 · tracked via the Priya Life Science EU tracker
Sponsor
AstraZeneca AB
Sponsor type
Pharmaceutical company
Therapeutic area
Bacterial Infections and Mycoses
Decision date
16/02/2026
Enrollment target
122
Sites
Greece, Spain, France, Germany, Italy, Hungary, Denmark, Sweden

Condition studied

Recurrence of Clostridioides difficile Infection

Investigational medicinal product(s)

Placebo for AZD5148AZD5148

Eligibility

Age group
18-64 years, 65+ years
Sex
Female, Male

Primary endpoint

First occurrence of recurrence of C. difficile infection

Endpoint detail

Sustained clinical cure (ie, achievement of initial clinical cure + no recurrent C. difficile infection)

Official registry record

This page summarises publicly available CTIS data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View 2025-521416-19-00 on CTIS ↗ ← All trials in the EU