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Clinical Trials in the EU / 2025-521108-23-00
Completed Phase III

A multicenter, randomized, double-blind, parallel group, placebo-controlled study of the efficacy and safety of early depemokimab initiation as add-on treatment in COPD patients with type 2 inflammation.

2025-521108-23-00 · tracked via the Priya Life Science EU tracker
Sponsor
Glaxosmithkline Research & Development Limited
Sponsor type
Pharmaceutical company
Therapeutic area
Respiratory Tract Diseases
Decision date
07/04/2026
Enrollment target
549
Sites
Germany, Belgium, Netherlands, Denmark, Spain, Greece, Poland, Hungary, France, Italy, Bulgaria, Romania

Condition studied

Chronic Obstructive Pulmonary Disease

Investigational medicinal product(s)

Novolizer Salbutamol 100 microgrammes/dosepoudre pour inhalationSterile 0.9% (w/v) sodium chloride solution in single-use PFS

Eligibility

Age group
18-64 years, 65+ years
Sex
Female, Male

Primary endpoint

Annualized rate of moderate/severe exacerbations.

Endpoint detail

Time to first moderate/severe exacerbation., Change from baseline in SGRQ total score (measured using the SGRQ-C) at Week 52., Change from baseline in E-RS: COPD total score at Week 52.

Official registry record

This page summarises publicly available CTIS data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View 2025-521108-23-00 on CTIS ↗ ← All trials in the EU