🇮🇪Ireland
16°C Partly Cloudy · Dublin
Live Updates
--:--:-- IST
Writer Login
Latest
Clinical Trials in the EU / 2025-520902-37-00
Completed Phase II

A Phase 2, Randomized, Double-Blind, Placebo-Controlled Study of V940 in Combination With Pembrolizumab and Chemotherapy as First-Line Treatment for Participants With Metastatic Squamous NSCLC (INTerpath-013)

2025-520902-37-00 · tracked via the Priya Life Science EU tracker
Sponsor
Merck Sharp & Dohme LLC
Sponsor type
Pharmaceutical company
Therapeutic area
Neoplasms
Decision date
23/03/2026
Enrollment target
59
Sites
Italy, Spain, Poland, France

Condition studied

Non-small cell lung cancer stage IV

Investigational medicinal product(s)

mRNA-4157DOCETAXELPACLITAXEL ALBUMIN-BOUNDKEYTRUDA 25 mg/mL concentrate for solution for infusion.CARBOPLATINPACLITAXELPlacebo to V940

Eligibility

Age group
65+ years, 18-64 years
Sex
Female, Male

Primary endpoint

Progression-free survival (PFS), Overall survival (OS)

Endpoint detail

Objective response rate (ORR), Duration of response (DOR), Number of Participants With ≥1 Adverse Event (AE), Number of Participants Discontinuing From Study Therapy Due to an AE

Official registry record

This page summarises publicly available CTIS data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View 2025-520902-37-00 on CTIS ↗ ← All trials in the EU